Conference Proceedings

Dr. Spencer Proctor

  • Proctor SD, and Mamo J.C.L Arterial fatty lesions have increased uptake of chylomicron remnants but not low density lipoprotein.’ Abstract in Proceedings of Annual Australian Atherosclerosis Society meeting, Canberra 1995.
  • Proctor SD, Yu K.C.W and Mamo J.C.L Chylomicron Remnants can penetrate arterial subendothelium and are Cytotoxic to surrounding cells. Abstract in Proceedings of Annual Australian Molecular Biology and biochemical Society, Canberra 1996.
  • Proctor SD, and Mamo J.C.L Separation and Quantitation of Apolipoprotein B48 and other apolipoproteins by Dynamic Sieving Capillary Electrophoresis. Abstract in Proceedings of Annual Australian Atherosclerosis Society meeting, Perth 1996.
  • Proctor SD, and Mamo J.C.L Separation and Quantitation of Apolipoprotein B48 and other apolipoproteins by Dynamic Sieving Capillary Electrophoresis. Published Abstract in Clinical Experimental Pharmacology and Physiology. 1997: (24).
  • Proctor SD, Pabla C.K. and Mamo J.C.L. Arterial uptake of chylomicrons and low density lipoproteins in insulin deficient rats and rabbits. Published Abstract in Proceedings of Annual Atherosclerosis Society 1997, Leura, Sydney, 1997.
  • Proctor SD, and Mamo J.C.L. In situ perfusion of fluorescent labeled chylomicron-remnants in rabbit carotid artery visualised by 3D-confocal microscopy. Published Abstract in Proceedings of International Atherosclerosis Symposium 1997 Paris France. Atherosclerosis 1997:134 (1,2); 270.
  • Proctor SD, Pabla C.K. and Mamo J.C.L. Arterial uptake of chylomicrons and low density lipoproteins in insulin deficient rats and rabbits. Published Abstract in Proceedings of International Atherosclerosis Symposium 1997, Paris, France. Atherosclerosis 1997:134 (1,2); 314.
  • Mamo JCL and Proctor SD. In situ perfusion of fluorescent labeled chylomicron remnants in rabbit carotid artery visualised by 3D-confocal microscopy. Abstract in Proceedings of Cardiology Society of Australia and New Zealand, 1998.
  • Mamo JCL, Smith S and Proctor SD. Retention of chylomicron remnants by arterial tissue; importance of an efficient clearance mechanism from plasma. Proceedings of European Atherosclerosis Postprandial Meeting, Utrecht, Netherlands 1999, Published as a full paper in Atherosclerosis. 1999 141 (Suppl 1.) S63-S69.
  • Proctor SD, and Mamo JCL. The contribution of chylomicron-remnants and LDL to the accumulation of cholesterol in the arterial wall following in-situ arterial perfusion. Abstract in Proceedings of Annual Australian Atherosclerosis Society Meeting, Adelaide, 2000.
  • Proctor SD, and Mamo JCL. The contribution of chylomicron-remnants and LDL to the accumulation of cholesterol in the arterial wall following in-situ arterial perfusion. Abstract in Proceedings of American Heart Association 2nd Annual Arteriosclerosis, Thrombosis and Vascular Biology Meeting, Arlington, Virginia 2001.
  • Proctor SD, and Mamo JCL. Determination of Lipoprotein efflux from arterial vessels using in-situ perfusion and three-dimensional confocal quantitation techniques. Abstract in Proceedings of Annual Australian Atherosclerosis Society Meeting, Fremantle, Perth WA 2001. (Clinical and Experimental Pharmacology and Physiology. 2001 Vol 29.)
  • Proctor SD, and Mamo JCL. Intimal retention of lipoprotein cholesterol in carotid arteries from watanabe rabbits. Selected as Oral Free Paper (#342) in proceedings of the 73rd Congress of European Atherosclerosis Society, 2002. Salzburg, Austria. (Atherosclerosis Suppl 2002 Vol 3.)
  • Proctor SD, Forbes JM and Mamo JCL. Arterial retention of cholesterol-rich lipoproteins derived from the intestine may be exacerbated by the formation of advanced glycation endproducts in diabetes. Abstract in Proceedings of Australian Health and Medical Research Congress (AHMR), Melbourne, VIC, November 2002.
  • Proctor, SD, Forbes, JM, and Mamo, JCL. Accumulation of intestinal cholesterol-rich remnant lipoproteins within arterial vessels may be exacerbated by advanced glycation endproducts and the co-localisation of proteoglycans in diabetes. Proceedings abstract for XIIIth International Symposium of Atherosclerosis, IAS Kyoto, Japan, October 2003 (Atherosclerosis Vol 4 (2) Suppl. Pg 54 1p-0156).
  • Proctor SD, Kelly SE, Russell JC. Dietary Arginine Silicate Inositol Complex Reduces Vasculopathy of Insulin Resistance in Atherosclerosis-Prone JCR:LA-cp Rats. Abstract in American Heart Scientific Sessions, Orlando, Florida, November, 2003.
  • Proctor, SD, and Mamo, JCL. Accumulation of intestinal cholesterol-rich remnant lipoproteins within arterial vessels may be exacerbated by advanced glycation endproducts and the co-localisation of proteoglycans in diabetes. Proceedings abstract in the proceedings of the Canadian Cardiovascular Congress, Toronto, Ontario, October 2003 (Canadian Journal of Cardiology Vol 19 (Suppl. A) #a883, 2003).
  • Dreher K, Proctor SD, Kelly SE, Russell JC Effect of oil combustion particles bioavailable constituents on ex vivo aortae recovered from healthy and early type-2 diabetic rats. Annual Canadian Physiological Society Meeting, January 2004, Silverstar Resort, Vernon, British Columbia, Canada.
  • Dreher K, Proctor SD, Kelly SE, Russell JC Effect of oil combustion particles bioavailable constituents on ex vivo aortae recovered from healthy and early type-2 diabetic rats. 43rd Annual Meeting of the Society of Toxicology, March 21-25, 2004, Baltimore, Maryland.
  • Proctor SD, Kelly SE, Russell JC. Dietary Arginine Silicate Inositol Complex Reduces Vasculopathy of Insulin Resistance in Atherosclerosis-Prone JCR:LA-cp Rats. ATVB 2004 Vol 24 (5), pg E-117 (Abstract#P384). Abstract in American Heart Scientific ATVB Sessions, San Francisco May 2004.
  • Proctor SD, and Mamo JCL. The Accumulation of Cholesterol Derived from Intestinal Chylomicron-Remnants Within Arterial Vessels is Associated with the Co-localization of Proteoglycans in Type-1 Diabetes’ ATVB 2004 Vol 24 (5), pg E-100 (abtrsct#P285). Abstract in American Heart Scientific ATVB Sessions, San Francisco May 2004.
  • Takechi R, Vine D, Russell JC and Proctor SD. Quantitation of apolipoprotein B48 in the atherosclerotic-prone, obese JCR:LA-cp rat using an enhanced chemiluminescence and western blot techniques. Abstract in proceedings of Canadian Lipoprotein Conference Banff, October 2004.
  • Proctor SD, Kelly SE and Russell JC. The dietary effects of conjugated linoleic acid and chromium picolinate on weight gain and vascular function in the obese JCR:LA-cp, early type-2 diabetic rat. Abstract in proceedings of Canadian Cardiovascular Congress. Calgary, Canada, October 2004. (Canadian Journal of Cardiology Vol 20 (Suppl. D) #a170, 2004).
  • Proctor SD, Takechi R, Russell JC and Vine DF. Impaired Postprandial Chylomicron Metabolism in the Atherosclerotic-prone, Obese JCR:LA-cp rat. Oral Abstract at the Canadian Physiological Society Annual Conference Quebec, Canada Jan. 2005.
  • Vine DF, Takechi R, Mangat R, Russell JC and Proctor SD. Impaired postprandial apolipoprotein-B48 metabolism predicts the severity of pre-diabetes in the atherosclerotic-prone, hyperinsulinemic JCR:LA-cp rat. Abstract in proceedings in the Canadian Lipoprotein Conference, Montebello, Quebec. September 2005.
  • Vine DF, Nzekwu U, Russell JC and Proctor SD. Impaired Metabolism of Chylomicrons and the corresponding post-prandial response of triglyceride and associated adipogenic hormones in the JCR:LA cp/cp rat model of obesity, insulin resistance and cardiovascular disease. Abstract (#260) in proceedings of the Canadian Diabetes Association Annual Conference, Edmonton, Alberta. October 2005. Canadian journal of Diabetes 2005 29(3):Suppl.1 pg328.
  • Proctor SD, Lu J and Russell JC. Conjugated linoleic acid supplementation protects against glomerulosclerosis in the obese and insulin-resistant JCR:LA-cp rat model. Abstract (#259) in proceedings of the Canadian Diabetes Association Annual Conference, Edmonton, Alberta. October 2005. Canadian journal of Diabetes 2005 29(3):Suppl.1 pg328.
  • Ruth M, Proctor SD, Journault N and Field C. Characterizing Immune Function and the Progression of Inflammation in the Obese and Insulin Resistant JCR:LA-cp Rat. Abstract (#261) in proceedings of the Canadian Diabetes Association Annual Conference, Edmonton, Alberta. October 2005. Canadian journal of Diabetes 2005 29(3):Suppl.1 pg329.
  • Vine DF, Russell JC and Proctor SD. Impaired metabolism of chylomicrons and corresponding post-prandial response can contribute to accelerated vascular disease in the JCR:LA cp/cp rat model of obesity and insulin resistance. Oral Abstract in proceedings of Canadian Cardiovascular Congress. Montreal, October 2005. Canadian Journal of Cardiology Vol 21:Suppl.C #a677, 2005.
  • Russell JC, Kelly SE and Proctor SD. Protective Micro and Macro Vascular Effects of Chromium Picolinate in the Prediabetic State. Oral abstract in the proceedings of the 3rd Annual World Congress on the Insulin Resistance Syndrome, San Francisco, November 2005. Diabetes and Vascular Disease Research 2005; Vol2:Issue 3, pg120.
  • Hassanali Z, Vine DF, Field C and Proctor SD. Acute effects of n-3 fatty acid supplementation on post-prandial lipid metabolism in the insulin-resistant JCR:LA-cp rat. Oral Abstract in the proceedings of the Canadian Physiological Society Annual Meeting. Alberta, Lake Louise February 2006
  • Vine DF, Russell JC and Proctor SD. Post-prandial dyslipidemia and poly-cystic ovarian syndrome in female corpulent JCR:LA-cp rats. Oral Abstract in the proceedings of the Canadian Physiological Society Annual Meeting. Alberta, Lake Louise February 2006.
  • Ruth MR, K MacNaughton, S Sokolik, S Goruk, DF Vine, SD Proctor & CJ Field, The Effect of Feeding Dietary EPA and DHA on Immune Cell characteristics and Cytokine Production in the Obese and Insulin Resistant JCR:LA-cp/cp Rat. Abstract in proceedings of the 7th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia
  • Hassanali Z, Vine DF, Field CJ and Proctor SD. Acute n-3 PUFA supplementation in the JCR:LA-cp rodent model of insulin resistance: Effects on post-prandial lipid metabolism. Abstract in proceedings of the 7th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia
  • Vine DF, Lu J, Russell JC, Field CJ and Proctor SD. Long term n-3 PUFA supplementation in the obese, insulin-resistant JCR:LA-cp rodent: effects on lipid profile, insulin-sensitivity and weight reduction. Abstract in proceedings of the 7th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia.
  • Mangat R, Dodd C , Scott PG, Russell JCR and Proctor SD. Vascular remodeling of atherogenic proteoglycans biglycan and decorin during metabolic syndrome. Canadian Lipoprotein Conference September 2006.
  • Lu J, Vine DF, Russell JC, Field CJ and Proctor SD. Chronic effects of n-3 polyunsaturated fatty acid (PUFA) supplementation on lipid and post-prandial lipoprotein metabolism in the JCR:LA-cp rodent during high cholesterol feeding. Canadian Lipoprotein Conference September 2006.
  • Nzekwu MMU, Su J, Jetha MM, Ball GDC and Proctor SD. Apolipoprotein B48, insulin resistance and dyslipidemia in overweight pre-pubertal children. Canadian Lipoprotein Conference September 2006.
  • Mangat R, Dodd C , Scott PG, Russell JCR and Proctor SD. Vascular remodeling of atherogenic proteoglycans biglycan and decorin during metabolic syndrome. Abstract in Canadian Cardiovascular Congress, October 2006. Canadian Journal of Cardiology Volume 22 Suppl #176.
  • Proctor SD. Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome. Invited Talk for A Biochemical Society Focused Meeting. Diet and cardiovascular health: Chylomicron remnants and their emerging roles in vascular dysfunction in atherogenesis. London, UK.  December 2006. (Online Pub).
  • Nzekwu MMU, Su J, Jetha MM, Ball GDC and Proctor SD. Apolipoprotein B48, insulin resistance, dyslipidemia and visceral fat in overweight pre-pubertal children. Invited Talk for A Biochemical Society Focused Meeting. Diet and cardiovascular health: Chylomicron remnants and their emerging roles in vascular dysfunction in atherogenesis. December 2006 (online pub).
  • Hassanali Z, Ruth MR, Gerdung CA, Goruk S, Lu J, MacNaughton K, Sokolik S, Russell JC, Vine DF, Ametaj B, Field CJ and Proctor SD. Acute n-3 PUFA supplementation in the JCR:LA-cp rodent model of insulin-resistance: Effects on post-prandial lipid metabolism and associated inflammatory response. Abstract in Biochemical Society Focused Meeting. Diet and cardiovascular health: Chylomicron remnants and their emerging roles in vascular dysfunction in atherogenesis. December 2006. (Online Pub.)
  • Wang Y, Lu J, Gerdung CA, Vine DF, Field CJ and Proctor SD. Acute supplementation of trans vaccenic acid improves plasma lipid profiles in the obese and insulin resistant JCR: LA-cp rat. Canadian Nutrition Congress Winnipeg, Canada, June 2007
  • Lu J, Vine DF, Ruth M, Glimm DR, Silva E, Field CJ and Proctor SD. Chronic effects of CLA:c-9,t-11-enriched butter oil and n-3 PUFA supplementation on dyslipidemia and renal pathophysiology in a obese rodent model. Canadian Nutrition Congress Winnipeg, Canada, June 2007.
  • Wang Y, Lu J, Gerdung CA, Vine DF, Field CJ and Proctor SD. Beneficial lipid lowering effects of acute trans vaccenic acid supplementation in the animal model of obesity and insulin-resistance JCR: LA-cp rat. CLA Network Summit Kananaskis, Canada, May 2007.
  • Duez H, Lamarche B, Valéro R, Pavlic M, Xiao C, Szeto L, Patterson B, Proctor SD and Lewis GF Regulation of Intestinal Lipoprotein Production by plasma Free Fatty acids in Humans. American Diabetes Association Sessions Abstract#3465 Chicago, USA, June 2007 (HSFC-GIA)
  • Pierce D, Heth D, Owczarczyk J, Russell JC and Proctor SD. Resistance of Obese-Prone Rats to Contingencies of Food Deprivation. Abstract in Proceedings of Association for Behavior Analysis International 2008 Convention Chicago, USA. (NSERC)
  • Proctor SD, Kelly S, Vine DF and Lopaschuk GD. Acute echo-cardiographical effect of APO-AI infusion in an animal model of left ventricular dysfunction and insulin resistance. Abstract in Proceedings of International Atherosclerosis Society Workshop on HDL, Greece, October 2007. (YIA CLC, HSFC)
  • Shi D, Russell JC, Proctor SD and Vine DF. Intestinal Chylomicronemia and Postprandial Dyslipidemia and in a Rodent Model of both Polycystic Ovarian and the Metabolic Syndrome. Abstract in Proceedings of Canadian Lipoprotein Conference Quebec, Canada, Oct. 2007. (NSERC)
  • Hassanali Z, England A, O’Neill D, MacNaughton K, Vine DF, Cheeseman C and Proctor SD. Characterization of intestinal villus morphology and corresponding chylomicron production in the JCR:LA-cp rodent, a model of the metabolic syndrome and post-prandial dyslipidemia. Abstract in Proceedings of Canadian Lipoprotein Conference Quebec, Canada, Oct. 2007. (NSERC/HSFC)
  • Mangat R, Dodd C , Shi D, Scott PG and Proctor SD. Enhanced binding of lymphatic chylomicron apolipoprotein-B48 particles from obese and insulin-resistant JCR:LA-cp rats to arterial proteoglycans. Abstract in Proceedings of Canadian Lipoprotein Conference Quebec, Oct. 2007. (HSFC)
  • J Su, A England, H Duez, M Pavlic, GF. Lewis, and Proctor. Increased accuracy to detect small apolipoprotein B48-remnant lipoproteins from whole plasma in subjects with fasting hyperinsulinemia. Canadian Lipoprotein Conference Quebec, Canada, Oct. 2007. (NSERC/HSFC)
  • Proctor SD, Kelly S, Vine DF and Lopaschuk GD. Echo-cardiographical effect of apoAI infusions in the hyper-insulinemic JCR:LA-cp rat, a spontaneous model of left ventricular dysfunction. Canadian Lipoprotein Conference Quebec, Canada, Oct. 2007. (YIA CLC, HSFC)
  • Wang Y, Lu J, Mangat R, MacNaughton K, Russell JC and Proctor SD. Effects of the long chain fatty acid: Medica 16 on post-prandial apolipoprotein-B48 metabolism in the JCR:LA-cp rodent and in CaCo-2 enterocytes. Abstract in Proceeding at Canadian Lipoprotein Conference Quebec, Canada Oct. 2007. (NSERC)
  • Pierce WD, Heth DC, Russell JC, Proctor SD. Resistance of Obese-Prone Rats to Contingencies of Food Deprivation. Abstract in Proceedings at the Annual Convention Association for Behavior Analysis International 2008, Chicago, USA. (NSERC)
  • Su J, Lambert J, Ryan E, Clandinin MT, Proctor SD. Post-Prandial Metabolism of Apolipoprotein B48-Containing Particles in Type-1 Diabetes Mellitus. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada, March 2008 Athero. Suppl. (HSFC, NSERC)
  • Wang Y, Vine DF and Proctor SD. Novel Hypolipidemic Properties of Trans-11 Vaccenic Acid is Partially due to Reduced Chylomicron Production and Improved Post-prandial lipemia in the JCR:LA-cp rat. Abstract in Proceedings of International Society for Chylomicrons in Disease, Lake Louise, Canada, March 2008.
  • Hassanali Z, England A, O’Neill D, MacNaughton K, Vine DF, Cheeseman C and Proctor SD. Intestinal Villi Hypertrophy is Associated with Over-production of Lymphatic Chylomicrons During Conditions of Obesity and Hyperinsulinemia in the JCR:LA-cp Rodent. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl. (HSFC, NSERC)
  • Mangat R, Wang F, MacNaughton K, Uwiera R and Proctor SD. Binding of Intestinally Derived Chylomicron-Remnants to Biglycan is Associated with an Increased Concentration of Particle Cholesterol Compared to Low-Density Lipoprotein. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl. (HSFC, NSERC)
  • Shi D, Russell JC, Proctor SD and Vine DF. Intestinal Chylomicronemia and Post-prandial Dyslipidemia in a Rodent Model of Polycystic Ovary Syndrome. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl. (HSFC, NSERC)
  • Vine DF, Kelly SE, MacNaughton K, Hassanali Z, Mangat R, Madsen K and Proctor SD. Exacerbated Production of Intestinal Lymph Chylomicrons is Associated with Increased Intestinal Transport of Cholesterol Curing Hyper-Insulinemia in the JCR:LA—cp Rodent. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl. (HSFC, Merck-Schering)
  • Wang Y, Lu J, Ruth MR, MacNaughton K, Kelly SE, Shi D, Goruk SD, Glimm D, Reaney MJ, Vine DF, Field CJ and Proctor SD. Novel Hypolipidemic Properties of Trans-11 Vaccenic Acid is Partially due to Reduced Chylomicron Production and Improved Post-Prandial Lipemia in the JCR:LA—cp Rat. Abstract in Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl. (DFC, NSERC, ALIDF)
  • Wang Y, Jacome-Sosa M, Lu J, Ruth MR, Goruk SD, Glimm D, Reaney MJ, Wright DC, Vine DF, Field CJ and Proctor SD. Newly described hypolipidemic benefits of trans-11 vaccenic acid in a rodent model of dyslipidemia and the metabolic syndrome. Abstract in Proceedings of 29th Western Nutrition Conference, Edmonton Canada, September 2008 and World Dairy Congress, Mexico City, November 2008. (DFC, NSERC, ALIDF)
  • Ye Wang, M. Miriam Jacome-Sosa, Kristina MacNaughton, Sandra E. Kelly, Danni Shi, Sue D. Goruk, David R. Glimm, David C. Wright, Donna F. Vine, Catherine J. Field and Proctor SD. Novel hypolipidemic properties of Trans-11 vaccenic acid and improvement in post-prandial lipaemia are due to reduced intestinal chylomicron production and hepatic lipogenesis in the JCR:LA-CP RAT.  Abstract in proceedings in the Canadian Lipoprotein Conference, Whistler, Canada, October 2008.
  • Jacome-Sosa MM*, Wang Y, Lu J, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Vine DF, Silva-Hernandez ER , Field CJ and Proctor SD. Dietary c-9, t-11 conjugated linoleic acid alone or in combination with t-11 vaccenic acid improve the lipid profile in a rodent model of metabolic syndrome.  Abstract in proceedings in the Canadian Lipoprotein Conference, Whistler, Canada, October 2008.  (ALIDF, DFC, NSERC)
  • Warnakula, R.Mangat, Y.Wang, R.Uwiera, K.MacNaughton, A. Jakura, J.C. Russell, D.F. Vine and S.D. Proctor. Effect of Ezetimibe and Simvastatin on Intestinal Lymphatic Chylomicron Over-Production in the Hyperinsulinemic JCR:LA-CP Rat.  Abstract in proceedings in the Canadian Lipoprotein Conference, Whistler, Canada, October 2008.  (Merck-Schering)
  • Proctor SD, Russell JC and Vine DF. Overproduction of Intestinal lymph chylomicrons is associated with hyperinsulinemia in the JCR:LA-cp rodent model of the metabolic syndrome.   Accepted at CSATVB, Toronto, Canada, October 2008. Invited talk.  (HSFC)
  • Jacome-Sosa M, Wang Y, Lu J, Ruth M, Goruk S, Reaney MJ, Glimm DR, Vine DF, Field CJ, Silva-Hernandez ER, Proctor SD. Hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid (CLA) alone or in combination with trans-11 vaccenic acid (VA) in a rodent model of dyslipidemia and the metabolic syndrome. Abstract in Proceedings of 29th Western Nutrition Conference and Alberta Diabetes Institute Annual Research Day Edmonton, Canada, September 2008 and World Dairy Congress, Mexico City, Mexico November 2008. (DFC, NSERC, ALIDF)
  • Pierce, W. D., Proctor, SD, Russell, J.C., and Heth, C.D. Restistence of Obese Prone Rats to the Challenge of Limited Food supply and heel Running.    Abstract in Proceedings of National Obesity Summit, Kananaskis, Canada, May 2009.  (ALIDF, HSFC, NSERC)
  • Lene N. Axelsen, Anne Louise Kjølbye, Henrik D. Pedersen, Jørgen S. Petersen, Proctor SD, Niels-Henrik Holstein-Rathlou3 and Gary D. Lopaschuk4. Glucagon and not exendin-4 improves cardiac function, glycolysis, and glucose oxidation in isolated hearts from insulin-resistant JCR:LA corpulent rats. Danish Cardiovascular Research Academy June 2009. (HSFC)
  • Mangat R, Wang Y, Warnakula S, Uwiera R, Vine DF and Proctor SD. Increased retention of intestinally derived chylomicron-remnants in arteries of JCR:LA-cp insulin-resistant rats ex-vivo is associated with binding to biglycan: Potential of vascular remodeling in accelerated cardiovascular disease during diabetes. Vascular Matrix Biology and Bioengineering workshop presented by the North American Vascular Biology Organization. Whistler, British Columbia. March 2009. (HSFC)
  • Vine, Z. Hassanali, R. Mangat, Y. Wang, R. Uwiera, J.C. Russell, Proctor SD. Exacerbated production of intestinal lymph chylomicrons is associated with increased transport of cholesterol and intestinal hypertrophy in the pre-diabetic JCR:LA-CP Rat.  Abstract in Proceedings of 3rd International Congress on pre-diabetes and the Metabolic Syndrome. Nice, France, April 2009.  (HSFC, NSERC)
  • M. Jacome-Sosa, Y. Wang, J. Lu, M.R. Ruth, S.D. Goruk, M.J. Reaney, D.R. Glimm, D.F. Vine, E.R. Silva-Hernandez, C.J. Field and Proctor SD. c-9, t-11 conjugated linoleic acid alone or in combination with t-11 vaccenic acid improves dyslipidemia and hepatic steatosis in a rodent model of the metabolic syndrome.  Abstract n Proceedings of the Canadian Society for Clinical Nutrition’s 8th Annual Scientific Meeting. Quebec City, Canada.  May 2009.  (ALIDF)
  • R. Ruth, Y. Wang, H.M. Yu, Proctor SD, D.F. Vine, and C.J. Field. The effects of vaccenic acid and elaidic acid on immune function in a rodent model of obesity and insulin resistance.  Abstract in Proceedings of the Canadian Society for Clinical Nutrition’s 8th Annual Scientific Meeting.  Quebec City, Canada.  May 2009.  (ALIDF)
  • Wang, M.M. Jacome-Sosa, M.R. Ruth, S.D. Goruk, M.J. Reaney, D.R. Glimm, D.C. Wright, D.F. Vine, C.J. Field, and Proctor SD. Novel hypolipidemic benefits of trans-11 vaccenic acid are partially contributed by reduced hepatic lipogenesis and lower intestinal chylomicron secretion in the JCR:LA-cp rat.  Abstract in Proceedings of the Canadian Society for Clinical Nutrition’s 8th Annual Scientific Meeting.  Quebec City, Canada.  May 2009.  (ALIDF)
  • Wang Y, Lu J, Ruth MR, Goruk SD, Reaney M, Glimm D, Vine DF, Field CJ and Proctor SD. Trans-11 vaccenic acid reduces hepatic lipogenesis and chylomicron secretion in the JCR:LA-cp Journal of Nutrition. Abstract in Proceedings of the 2009 Canadian Lipoprotein Conference in Windsor, Canada, October 2009.  (ALIDF)
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Trans-11 vaccenic acid bioavailability from different food sources and effects on intestinal chylomicron production in the JCR:LA-cp rodent model”.  Abstract in proceedings of the Canadian Lipoprotein Conference in Windsor, Canada, October 2009. (ALIDF)
  • Field CJ, Ruth MR, Yu H, Wang Y, Proctor SD, and Vine DF. The beneficial effect of feeding a trans fatty acid, vaccenic acid, on immune function in a rodent model of obesity and insulin resistance. Abstract in Proceedings of International Diabetes Federation in Montreal, Canada, October 2009.  (BIC, ALIDF)
  • Mangat R, Vine DF, Forbes JM, Cooper ME, Mamo JCL and Proctor SD. Arterial retention of remnant lipoproteins is decreased by a comibation of ezetimibe and simvastatin in insulin resistant JCR-LA-cp rats. Abstract in Proceedings of the Canadian Society of Atherosclerosis Thrombosis and Vascular Biology in Edmonton, Canada, October 2009.  (ALIDF)
  • Pierce DW, Diane A, Heth DC, Russell JC, Proctor SD. Reduction of Hypertriglyceredimia and Renal Vascular Dysfunction in Insulin Resistant, Atherosclerosis-Prone JCR:LA-cp rats by Rimonabant. Abstract in proceedings of AFERO in Paris, France, January 2010. (NSERC, ALMA)
  • Warnakula S, Mangat R, Y Wang, K MacNaughton, Russell JC, Uwiera R, Vine DF, and Proctor SD. Combination therapy of ezetimibe and simvastatin ameliorates myocardial lesion frequency and synergistically reduces arterial retention of remnant lipoproteins in insulin-resisteant JCR:LA-CP rats.  Abstract in proceedings of Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions in San Francisco, USA, April 2010.
  • Borthwick F, Warnakula S, Mangat R, Uwiera R and Proctor SD. Acute HDL infusion reduces arterial cholesterol deposition and myocardial lesion frequency in the hyperlipidemic JCR:LA-cp rat model of the Metabolic Syndrome. Abstract in proceedings of IAS HDL Workshop in Whistler, Canada, May 2010.
  • Pierce DW, Diane A, Heth DC, Russell JC, Proctor SD. Feeding history and genotype increase survival of rats exposed to contingencies of food restriction and food-related travel.  Abstract in Proceedings of ABA International 36th Annual Convention in San Antonio, USA May 2010.  (NSERC, ALMA)
  • Jacome-Sosa M, Wang y, J. Lu, M.R. Ruth, S.D. Goruk,J. Reaney, Glimm DR, Vine DF, E.R. Silva-Hernandez, C.J. Field and S.D. Proctor. Synergistic effects of natural trans-fats, cis-9, trans-11 conjugated linoleic acid (CLA) and trans-11 vaccenic acid in the JCR:LA-cp rat. Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010. (ALIDF)
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Trans-11 vaccenic acid is bioavailable from different food sources and reduces intestinal chylomicron secretion in the JCR:LA-CP rat model. Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010. (ALIDF)
  • Borthwick F, Lu J, Hassanali Z, Wang Y, Mangat R, Ruth M, Shi D, Russell JC, Field CJ, Jaeschke A, Vine DF and Proctor SD. Dietary N-3 PUFA improves post-prandial metabolism in the insulin resistant JCR:LA-CP rat by lowering enterocytic APO-B48 production and lymphatic cholesterol. Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010. (ALIDF)
  • Mangat R, Vine DF, Forbes JM, Cooper ME, Mamo JCL and Proctor SD. Increased risk of cardiovascular disease in type 1 diabetes: Increased arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans. Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010. (Merck-Schering, ALIDF)
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Dietary Trans-11 Vaccenic Acid Increases Intestinal PPAR Alpha and Gamma Expression in the JCR:LA-cp Rat. Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010. (Merck-Schering, ALIDF)
  • Pendlebury C, Nzekwu MMU, Vine DF, Beaulieu C, Jetha MM, Ball GDC, Proctor SD. Elevated chylomicron concentration in obese pre-pubertal children may be an early marker of cardiovascular disease risk.  Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010. (Merck-Schering, ALIDF)
  • Rueda-Clausen C.F, Dolinsky V.W, Morton J.S, Proctor, S.D, Dyck J.R.B, and Davidge S.T. Intrauterine growth restriction increases the susceptibility to diet-induced obesity and insulin resistance.  Abstract in proceedings of 2nd Canadian Obesity Student Meeting in Ottawa, Canada, June 2010.
  • Wadowski M, Goruk S, Wang Y, Wright D, Proctor, SD, Field CJ. Feeding Vaccenic Acid reduces expression of inflammatory and regulatory cytokines in perirenal fats pad of obese insulin resistant JCR:LA-cp/cp rats. Abstract in proceedings of 2nd Canadian Obesity Student Meeting in Ottawa, Canada, June 2010.
  • Rodríguez Dimitrescu A, Proctor, Jacobs RL, Vine DF.  Lipid metabolism in the JCR:LA rodent model of polycystic ovary síndrome.  Effects of flutamide and metformin.  Abstract in proceedings of Canadian Lipoprotein Conference, Niagara on the Lake, Canada, October 2010.
  • Borthwick F, Mangat R, Uwiera RR, Vine DF, Proctor SD. The retention (ex-vivo) of both intestinal and hepatically-derived remnant lipoproteins is increased in arterial vessels from insulin resistant JCR:LA-cp rats, but efflux (removal) is differential.  Abstract in proceedings of Canadian Lipoprotein Conference, Niagara on the Lake, Canada, October 2010.
  • Pierce DW, Diane A, Heth DC, Russell JC, Proctor SD. Feeding history increases food-related travel and survival of obese prone   Abstract in proceedings of 37th Association for Behavior Analysis International, Annual Convention, Denver, CO, USA 2011. (NSERC, ALMA)
  • Mangat R, Warnakula S, Borthwick F, Uwiera RR, Russell JC, Vine DF and Proctor SD Both arterial retention and vascular efflux of remnant lipoprotein cholesterol contribute to CVD risk during insulin resistance in a rodent model of the metabolic syndrome, the JCR:LA-cp rat. Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions in Chicago, USA, April 2011.
  • Rodríguez Dimitrescu A, Proctor, Jacobs RL, Vine DF. Polycystic Ovary Syndrome: Exploring Mechanisms of Atherogenic Dyslipidemia in a Rodent Model.  Canadian Diabetes Association Professional Conference and Annual Meeting. Toronto, Canada. October 2011.
  • Dromparis P, Sutendra G, Bowers L, Haromy A, Hashimoto K, Stenson TH, Proctor S, Michelakis ED, and McMurtry MS. Pioglitazone reduces angiogenesis by altering mitochondrial function and reducing HIF-1 activation.  American Heart Association, Scientific Sessions.  Orlando, USA. November 2011.
  • Ye Wang, M.Miriam Jacome-Sosa, Reaney MJ, Shen J, Scott S, Field CJ, Vine DF and D Proctor. Ruminant trans fat trans-11 vaccenic acid is more bioavailable from a triglyceride source and regulates intestinal lipid metabolism via peroxisome proliferator activated receptor-dependent pathways in a rodent model of dyslipidemia and metabolic syndrome. Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Borthwick F, Rabban Mangat, Vine DF, Proctor SD. Statin treatment upregulates intestinal lipid secretion pathways in the dyslipidemic, insulin resistant JCR:LA-cp Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Mangat R, Borthwick F, Uwiera RR, Russell JC, Vine DF, Proctor SD. Remodeling of the vessel wall during insulin resistance may explain preferential retention of cholesterol-rich remnant lipoproteins and increased CVD in the JCR:LA-cp rat. Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Borthwick F, Mangat R, Vine DF, Proctor SD. Statin treatment upregulates intestinal lipid secretion pathways in a rodent model of insulin resistant and CVD, the JCR:LA-cp rat. International Symposium on Atherosclerosis Conference.  Sydney, Australia.  March 2012.
  • Mangat R, Borthwick F, Uwiera RR, Russell JC, Vine DF, Proctor SD. Remodeling of the vessel wall during insulin resistance may explain preferential retention of cholesterol-rich remnant lipoproteins and increased CVD in the JCR:LA-cp rat. International Symposium on Atherosclerosis Conference.  Sydney, Australia.  March 2012.
  • Wang, M. Jacome-Sosa, MR Ruth, MJ Reaney, J. Shen, CJ Field, DF Vine, SD Proctor. Dairy trans-fat, trans-11 vaccenic acid, is a natural nuclear receptor (PPAR) ligand and synergistically improves dyslipidemia in combination with conjugated linoleic acid in the diet. Therapeutic Applications of Functional Foods Conference. Winnipeg, MB. May 2012.
  • Ye Wang, M.Miriam Jacome-Sosa, Reaney MJ, Shen J, Scott S, Anderson HD, Field CJ, Vine DF and Proctor SD. Ruminant trans-11 vaccenic acid activates peroxisome proliferator-activated receptor-dependent pathways and improves cardiomyocyte hypertrophy associated with the metabolic syndrome. International Society for the Study of Fatty Acids and Lipids. Vancouver, Canada.  May 2012.
  • Jacome-Sosa MM, Wang Y, Borthwick F, Jacobs RL, Nelson R, Reaney MJ, Shen J, Quiroga AD, Lehner R and Proctor SD. Ruminant trans-11 vaccenic acid decreases fasting and post-prandial hypertriglyceridemia by reducing both hepatic and intestinal TG secretion and associated genes in a rat model of the metabolic syndrome.   International Society for the Study of Fatty Acids and Lipids. Vancouver, Canada.  May 2012.
  • Borthwick F, Ullrich T, Mangat R, Jacome-Sosa MM, Kelly SE, Proctor SD. Vine DF. Niacin increases the secretion of intestinal derived lipid-poor HDL particles in a rat model of insulin resistance.  The American Society for Biochemistry and Molecular Biology.  Banff, Canada.  September 2012.
  • Mangat R, Ullrich T, Borthwick F, Jacome M, Kelly SE, Proctor SD, Vine DF. Niacin attenuates intestinal chylomicron over-secretion in the JCR:LA-cp rat: a model of metabolic syndrome and insulin resistance.  The American Society for Biochemistry and Molecular Biology.  Banff, Canada.  September 2012.
  • Wu S, Borthwick F, Mangat R, Vine DF, Proctor SD. Over-secretion of intestinal apoB48 lipoproteins is associated with decreased enterocytic heat shock protein-90 in a rat model of insulin-resistance. The American Society for Biochemistry and Molecular Biology.  Banff, Canada.  September 2012.
  • Wang Y, Diané A, Kelly SE, Jacobs RL, Proctor SD, Vine DF.  Metformin and flutamide attenuate plasma and lymphatic apoB48 and apoB100 concentrations in the JCR:LA-cp rat: a model of insulin resistance and polycystic ovary syndrome.  The American Society for Biochemistry and Molecular Biology.  Banff, Canada.  September 2012.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin beneficially alters the secretion of intestinal derived TRL and HDL in a rat model of insulin resistance. Arteriosclerosis, Thrombosis and Vascular Biology 2013 Scientific Sessions.  Florida, USA.  May 2013.
  • Diané Abdoulaye, Pierce W David, Faye Borthwick, Jacob René, Nelson Randal, Heth Donald C, Russell James C, Vine Donna F, Proctor Spencer D. Differential Expression of Hypothalamic Metabolic and Inflammatory Genes in Response to Short-Term Calorie Restriction in Young Obese- and Lean-prone JCR Rats. 3rd Canadian Obesity Summit.  May 2013.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin simultaneously benefits the secretion of both intestinal chylomicrons and HDL in a rat model of insulin resistance by stimulating the PPAR alpha pathway in enterocytes.  Canadian Lipoprotein Conference.  de Mont Tremblant, Quebec. September 2013.
  • Jacome MM, Mangat R, Reaney MJ, Vine D, Banni S and Proctor SD. Beneficial tissue specific regulation of endocannabinoids by vaccenic acid during insulin resistance.  Canadian Lipoprotein Conference.  de Mont Tremblant, Quebec. September 2013.
  • Faye Borthwick, Rabban Mangat, Samantha Warnakula, Miriam Jacome, Donna F Vine, Spencer D Proctor. Simvastatin treatment results in a compensatory upregulation of lipid secretion by the intestine in a rodent model of the metabolic syndrome.  Canadian Lipoprotein Conference.  de Mont Tremblant, Quebec. September 2013.
  • Abdoulaye Diané, Maria Kupreeva David Pierce, Sandra Kelly, Spencer D Proctor and Donna F. Vine. Lifestyle and pharmaceutical combination therapy on cardiometabolic risk and reproductive indices in rodent model of pre-diabetes and polycystic ovary syndrome. 16th Annual CDA/CSEM Professional Conference & Annual Meetings Montreal, Quebec. October 2013.
  • Kupreeva M, Wang F, Diane A, Kelly SE, Ghosh M, Jacobs RL, Proctor SD, Vine DF. Differentiating the Role of Testosterone and Insulin Mediated Effects on Lipid Metabolism in a Rodent Model of Prediabetes and Polycystic Ovary Syndrome. 16th Annual CDA/CSEM Professional Conference & Annual Meetings Montreal, Quebec. October 2013.
  • Borthwick F, Mangat R, Warnaula S, Jacome M, Vine DF, Proctor SD. Simvastatin and ezetimibe have opposing regulation on intestinal cholesterol absorption and trans intestinal cholesterol excretion (TICE) during metabolic syndrome.  82nd European Atherosclerosis Society Congress.  Madrid, Spain.  May 2014.
  • Mangat R, Borthwick F, Jacome M, Vine DF, Voroz S, Proctor SD. Reduced ‘egress’ of remnant lipoproteins from arterial tissue relative to LDL during insulin resistance may explain a preferential role in atherosclerosis progression.  Arteriosclerosis, Thrombosis and Vascular Biology.  Toronto, Canada.  May 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin beneficially alters the secretion of intestinal HDL in a rat model of insulin resistance by opposing effects on PPAR alpha and TNF alpha.  Arteriosclerosis, Thrombosis and Vascular Biology-Scientific Sessions.  Toronto, Canada.  May 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated microRNA Profile in Rat Model of Insulin Resistance.  Canadian Nutrition Society, St. Johns, Canada June 2014.
  • Mangat R, Borthwick F, Ullrich T, Nelson R, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated microRNA Profile in a Rat Model of Insulin Resistance.  FASEB Journal.  Federation of American Societies for Experimental Biology (FASEB).  Molecular Mechanisms of Intestinal Lipid Transport and Mechanism.  Keystone, USA.  July 2014.
  • Mangat R, Borthwick F, Warnakula S, Jacome-Sosa MM,  Vine D, Proctor SD.  Simvastatin and ezetimibe have opposing regulation on intestinal cholesterol absorption and trans intestinal cholesterol excretion (tice) during metabolic syndrome.  American Heart Association Scientific Session.  Toronto, Canada.  Atherosclerosis Supplements 2014 Aug; 235(2):e185.
  • Mangat R, Warnakula S, Borthwick F, Vine DF, Proctor SD. Simvastatin and Ezetimibe are opposing in their Regulation of Intestinal Cholesterol Absorption and Trans Intestinal Cholesterol Excretion (TICE) in a Rodent Model of the Metabolic Syndrome.  Canadian Lipoprotein Conference.  Saskatoon, Canada.  October 2014.
  • Diane A, Kupreeva M, Jacobs RL, Proctor SD, Vine DF. Androgen and insulin mediated effects on lipid metabolism in a rodent model of polycystic ovary syndrome (PCOS). Canadian Lipoprotein Conference, Saskatoon, Canada.  2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin alters the secretion of intestinal lymphatic HDL and associated miRNA profile in a rat model of insulin resistance.  Canadian Cardiovascular Congress.  Vancouver, Canada.  October 2014.
  • Mangat R, Borthwick F, Vine DF, Proctor SD. Lymphatic HDL can act as a donor for TICE and this pathway is impaired under conditions of insulin resistance and high fat diet.  DEUEL Conference. Monterey, USA.  March 2015.
  • Mangat R, Borthwick F, Vine DF, Proctor SD. Lymphatic derived HDL Is An Effective Donor For The Trans-Intestinal Cholesterol Efflux Pathway That Is Impaired During Insulin Resistance.  ATVB 2015.  San Francisco, USA.   May 2015.
  • Michaelann Wilke, Maximova K, Henderson M, Levy E, Paradis G, O’Loughlin J, Tremblay A, Proctor SD. Adiposity in Children and early sub-clinical CVD risk:  ApoB48 has a stronger association with central fat than classic lipid markers.  International Symposium on Atherosclerosis. Amsterdam, The Netherlands.  May 2015.
  • Ooi TC, Krysa J, Abujrad H, Mayne J, Henry K, Cousins M, Raymond A, Favreau C, Taljaard M, Chretien M, Mbikay M, Proctor S, Vine D. The Effect of PCSK9 Loss of Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response.  Kern Lipid Conference.  Vail, USA.  August 2015.
  • Ooi TC, Krysa J, Abujrad H, Mayne J, Henry K, Cousins M, Raymond A, Favreau C, Taljaard M, Chretien M, Mbikay M, Proctor S, Vine DF. The Effect of PCSK9 Loss of Function Variants on the Postprandial lipid and ApoB-Lipoprotein Response.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Mangat R, Nelson R, Vine DF, Proctor SD. Intestinal HDL apoA-I secretion is reduced and associated miRNAs are altered during insulin resistance that is improved by Niacin.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Soto Y. Mangat R, Vine DF, Proctor SD.  Application of a novel anti-proteoglycan antibody to inhibit acute arterial retention of remnant lipoproteins in a rat model of insulin resistance.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Wilke M, Maximova K, Henderson M, Levy E, Paradis G, O’Loughlin J, Tremblay A, Proctor SD. ApoB48 has a stronger association than classic lipid markers with increasing central fat mass in pre-pubertal children. Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Anankrishnanthin G, Jacobs R, Proctor SD, Vine D. Testosterone differentially modulates triglyceride and cholesterol metabolism in a rodent model of polycystic ovary syndrome and the metabolic syndrome. Canadian Society Endocrinology and Metabolism. World Diabetes Congress. Vancouver, Canada, December, 2015.
  • Diane A, Kupreeva M, Proctor SD, Pierce DW and Vine DF. Exercise and metformin-flutamide therapy improve cardiometabolic and endocrine-reproductive outcomes in a rodent model of PCOS and metabolic syndrome. World Diabetes Congress, Canadian Society of Endocrinology and Metabolism.  Vancouver, Canada, December, 2015.
  • Diane, R. Mangat, SE Kelly, MA Fontaine, VP. Singh J. Li, B. Willing, D. Vine, SD. Proctor SD. Low birth weight increases intestinal lipid absorption during insulin sensitive and insulin resistant conditions in pigs. World Diabetes Congress, Vancouver Canada. December 2015.
  • Mangat R, Vine DF, Proctor SD. Trans-intestinal cholesterol efflux is reduced and associated with HDL-C in diabetic and insulin resistant dyslipidemia.  Canadian Society Endocrinology and Metabolism.  World Diabetes Congress. Vancouver, Canada.  December 2015.
  • Ananthakrishnan G, Proctor SD, Ghosh M, Jacobs RL, Vine DF. Androgens Modulate Plasma and Intestinal Triglyceride and Cholesterol Metabolism in a PCOS-Prone Rodent Model. The Endocrine Society’s 98th Annual Meeting & Expo.  Boston USA.  April 2016.
  • Soto Y, Mangat R, Vazquez AM, Proctor SD. Novel Chimeric Anti-proteoglycan Antibody Inhibits Arterial Retention of Proatherogenic Lipoproteins in a Rat Model of Insulin Resistance.  Arteriosclerosis, Thrombosis and Vascular Biology, Peripheral Vascular Disease.  Nashville, USA. May 2016.
  • Diané A, Kupreeva M, Pierce WD, Kelly S, Proctor SD and Vine DF. Benefits of Early Energy Restriction and Voluntary exercise in an Obese PCOS-Prone Rodent Model.  United Scientific Group, Obesity & Chronic Diseases-2016.  Las Vegas, USA. July 2016.
  • Krysa JA, Vine DF, Beilin LJ, Burrows S, Huang R-C, Mori T, Proctor SD. The Relationship of Fasting Plasma ApoB48 to Cardiometabolic Risk Factors in Adolescents. School of Medicine and Pharmacology Seminar Series, University of Western Australia, July 2016.
  • Rabban Mangat, Yosdel Soto, Ana Maria Vazquez and Spencer Proctor. Arterial remnant lipoprotein retention is inhibited by an anti-proteoglycan antibody in a rat model of insulin resistance.  41st Canadian Lipoprotein Conference 2016.  John’s, Canada.  September 2016.
  • Ananthakrishnan G, Proctor SD, Ghosh M, Jacobs RL, Vine DF. Androgens modulate intestinal absorption and synthesis of lipids contributing to impaired lipid metabolism in a rodent model of Polycystic Ovary Syndrome and Metabolic Syndrome.  The Canadian Society of Endocrinology and Metabolism Conference and Annual Meeting.  Ottawa Canada.  October 2016.
  • Yosdel Soto, Rabban Mangat, Ana María Vázquez and Spencer Proctor. Novel anti-PG antibody inhibits arterial retention of pro-atherogenic lipoproteins in a rat model of insulin resistance. Immuno-Metabolic Mechanisms of Atherosclerosis Conference, Novel critical mediators and therapeutic targets, Cancun, Mexico. March 2017.
  • Jacqueline A Krysa, Donna F Vine, Lawrence J Beilin, Sally Burrows, Rae-Chi Huang, Trevor A Mori, Spencer D Proctor. The relationship of fasting plasma apoB48 to cardiometabiolic risk factors in adolescents. Canadian Obesity Summit., Banff, Canada. April 2017.
  • *Krysa JA, Vine DF, Beilin LJ, Burrows S, Huang R-C, Mori TA, Proctor SD. ApoB48-lipoprotein Remnants are Associated with Increased Cardiometabolic Risk in Adolescents. Oral Presentation. FASEB Summer Research Conference, Snowmass, Aspen, CO, United States. July 2017.
  • Kupreeva M, Proctor SD, *Vine DF. Targeting insulin and androgen receptor signaling pathways differentially modulates insulin-glucose, lipid and ApoB-lipoprotein metabolism, and reproductive-endocrine function in a PCOS-prone rodent model. CSEM 2017: Androgen Excess and PCOS Society, Edmonton, Canada. November 2017.
  • Spencer Proctor and Geoff Ball. Invited Speaker (Internal Seminar Series). Canadian Child Health Clinician Scientist Program, University of Alberta Chapter. Perspectives on Publishing and Reviewing in Discovery, Clinical & Health Services Research. Feb 2018.
  • Jacqueline Krysa, Donna Vine and Spencer Proctor. ApoB-Remnant Dyslipidemia and High-Fat Meal Intolerance Exacerbates Cardiometabolic Risk in Overweight Children. Oral presentation, Canadian Lipoprotein Conference, Toronto, June 2018
  • Yosdel Soto, Rabban Mangat, Sylvie Marleau, Ana M. Vázquez and Spencer D. Proctor. Novel anti-proteoglycan antibody inhibits subendothelial lipoprotein retention and prevents cardiac hypertrophy in a rat model of insulin resistance. Oral presentation, Canadian Lipoprotein Conference, Toronto, June 2018
  • Spencer Proctor. Impact of Diabetes on Remnant (and apoAI) Metabolism: Role for Niacin. Invited Speaker, International Symposia for Atherosclerosis, Toronto, June 2018
  • Jacqueline Krysa, Donna Vine and Spencer Proctor. ApoB-Remnant Dyslipidemia and High-Fat Meal Intolerance Exacerbates Cardiometabolic Risk in Overweight Children Oral presentation, International Symposia for Atherosclerosis, Toronto, June 2018
  • Yosdel Soto, Rabban Mangat, Sylvie Marleau, Ana M. Vázquez and Spencer D. Proctor. Novel anti-proteoglycan antibody inhibits subendothelial lipoprotein retention and prevents cardiac hypertrophy in a rat model of insulin resistance. Oral presentation, International Symposia for Atherosclerosis, Toronto, June 2018.
  • Donna Vine, Jacqueline Krysa, Geoff Ball and Spencer Proctor. Fasting Plasma ApoB-Remnant Lipoproteins Can Predict Impaired Non-Fasting Lipid and ApoB-Lipoprotein Metabolism in Healthy-Weight and Overweight Children. Canadian Society for Endocrinology and Metabolism, October 2018 Halifax, Nova Scotia.
  • Donna F Vine, Sally Burrows, Rae-Chi Huang, Lawrence J Beilin,T, Spencer D Proctor, Trevor A Mori. ApoB48-Remnant Lipoproteins are Associated with Increased Cardiometabolic Risk in a Cohort of Adolescents with and without Polycystic Ovary Syndrome. Canadian Society for Endocrinology and Metabolism, October 2018 Halifax, Nova Scotia.
  • Yosdel Soto, Rabban Mangat, Sandra Kelly, Ana María Vázquez and Spencer Proctor. Anti-proteoglycan antibody inhibits arterial retention of proatherogenic lipoproteins in a rat model of insulin resistance. (Poster Presentation) Immunometabolism Satellite to the European Atherosclerosis Society Annual Meeting, Maastricht, Netherlands May 25-26, 2019.
  • Yosdel Soto,Rabban Mangat, Sandra Kelly, Ana María Vázquez and Spencer Proctor. Novel anti-glycosaminoglycan monoclonal antibody prevents cardiac hypertrophy in a rat model of metabolic syndrome. (Highlighted Abstract oral presentation) European Atherosclerosis Society Annual Meeting, Maastricht, Netherlands, May 26-29, 2019.
  • Donna F. Vine, Spencer D. Proctor. Metformin-Fish Oil Adjunct Therapy Improves Atherogenic Dyslipidemia: ApoB-Remnant Lipoprotein and Triglyceride Levels in Women with Polycystic Ovary Syndrome.  Diabetes Canada, 21st Annual Professional Conference and Annual Meeting, Winnipeg, MB, October 2-5, 2019.
  • Yosdel Soto, Rabban Mangat and Spencer Proctor. A potential idiotypic vaccine for the treatment of atherosclerosis based on a chimeric mouse/human anti-sulfated glycosaminoglycans antibody. Vascular Summit, Joint Annual Conference of the Canadian Lipoprotein Conference and the Canadian Society for Atherosclerosis, Thrombosis and Vascular Biology. Banff, AB, October 2019.
  • Jacqueline Krysa, Ming Ye, Dean Eurich, Spencer Proctor. Non-Fasting Remnant Cholesterol in Alberta’s Tomorrow Project: Implications for CVD Risk Prediction. Vascular Summit, Joint Annual Conference of the Canadian Lipoprotein Conference and the Canadian Society for Atherosclerosis, Thrombosis and Vascular Biology. Banff, AB, October 2019.

Dr. Donna Vine

  • Vine DF, Croft KD, Beilin LJ and Mamo JCL. The effect of dietary oxysterols on lipoprotein oxysterols levels and susceptibility of lipoproteins to oxidation in the rabbit. Combined Biological Society of Western Australia 1994.
  • Vine DF, Croft KD, Beilin LJ and Mamo JCL. Absorption and incorporation of dietary oxysterols into lymph. Oral Abstract in the Proceedings for the Free Radical Society 1995.
  • Vine DF, Croft KD, Beilin LJ and Mamo JCL. The intestinal absorption and in-vivo kinetics of chylomicrons containing dietary oxysterols. Australian Atherosclerosis Society Annual Conference 1996.
  • Vine DF ,Croft KD, Beilin LJ and Mamo JCL. The short-term feeding of dietary oxysterols increases triglyceride rich lipoprotein oxysterols and their susceptibility to oxidation, and increases aortic cholesterol concentration. Australian Atherosclerosis Society Annual Conference 1996.
  • Vine DF The intestinal absorption and in-vivo kinetics of chylomicrons containing dietary oxysterols. Mark Liveris Health Science Seminars 1996.
  • Vine DF, Croft KD, Beilin LJ and Mamo JCL. Oxysterols alter the apolipoprotein complement of chylomicrons and chylomicron remnants effecting their metabolism in-vivo. Australian Atherosclerosis Society Annual Conference 1997.
  • Vine DF, Croft KD, Beilin LJ and Mamo JCL.); Absorption and in-vivo kinetics of oxysterols in lymph chylomicrons. XI International Atherosclerosis Symposium, Paris, France, August 1997
  • Vine DF, Charman SA, Charman WN and Porter CJH. The effect of a high fat diet on the transport of passive and active marker compounds in excised rat intestinal tissues. Globalization of Pharmaceutics Education Network, Uppsala, Sweden, September 2000.
  • Vine DF, Charman SA, Charman WN and Porter CJH. Impact of post-prandial state on the apparent permeability of marker compounds in excised rat intestinal tissues. Globalization of Pharmaceutics Education Network, Uppsala, Sweden, September 2000.
  • Vine DF The Science of Functional Foods. Future Science Conference, Murdoch University, December 2001 (Oral by invitation).
  • Vine DF, Nzekwu U, Russell JC and Proctor SD. Impaired Metabolism of Chylomicrons and the corresponding post-prandial response of triglyceride and associated adipogenic hormones in the JCR:LA cp/cp rat model of obesity, insulin resistance and cardiovascular disease. Abstract (#260) in proceedings of the Canadian Diabetes Association Annual Conference, Edmonton, Alberta. October 2005. Canadian journal of Diabetes 2005 29(3):Suppl.1 pg328
  • Proctor SD and Vine DF. Insights into the impact of CLA in the atherosclerosis-prone obese JCR:LA-cp rat model. Invited Oral presentation in the proceedings of Conference on the Role of CLA in Human Health (Canadian National Network for CLA). Winnipeg, October 2004.
  • Takechi R, Vine DF, Russell JC and Proctor SD. Quantitation of apolipoprotein B48 in the atherosclerotic-prone, obese JCR:LA-cp rat using an enhanced chemiluminescence and western blot techniques. Oral Abstract in proceedings of Canadian Lipoprotein Conference Banff, October 2004.
  • Proctor SD, Takechi R, Russell JC and Vine DF. Impaired Postprandial Chylomicron Metabolism in the Atherosclerotic-prone, Obese JCR:LA-cp rat. Oral Abstract at the Canadian Physiological Society Annual Conference Quebec Jan 2005.
  • Vine DF, Russell JC and Proctor SD. Post-prandial dyslipidemia and poly-cystic ovarian syndrome in female corpulent JCR:LA-cp rats. Oral Abstract in the proceedings of the Canadian Physiological Society Annual Meeting. Alberta, Lake Louise February 2006.
  • Hassanali Z, Vine DF, Field CJ and Proctor SD. (2006) Acute n-3 PUFA supplementation in the JCR:LA-cp rodent model of insulin-resistance:effects on post-prandial lipid metabolism. Canadian Physiolgoical Society, January 2006, Lake Louise, Canada.
  • Ruth MR, MacNaughton K, Sokolik S, Goruk S, Vine DF,  Proctor SD & Field CJ, The Effect of Feeding Dietary EPA and DHA on Immune Cell characteristics and Cytokine Production in the Obese and Insulin Resistant JCR:LA-cp/cp Rat. Abstract in proceedings of the 7Th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia.
  • Hassanali Z, Vine DF, Field CJ and Proctor SD. Acute n-3 PUFA supplementation in the JCR:LA-cp rodent model of insulin resistance: Effects on post-prandial lipid metabolism. Abstract in proceedings of the 7Th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia.
  • Vine DF, Lu J, Russell JC, Field CJ and Proctor SD. Long term n-3 PUFA supplementation in the obese, insulin-resistant JCR:LA-cp rodent: effects on lipid profile, insulin-sensitivity and weight reduction. Abstract in proceedings of the 7Th Congress of the International Society for the Study of Fatty Acids and Lipids, July 2006, Cairns, Australia.
  • Vine DF and Proctor SD. Oral Abstract:Characterization of PCOS and intestinal contribution to CVD risk in female JCR:LA-cp rats. Alberta Diabetes Institute Retreat, Edmonton, Alberta, September 2006.
  • Lu J, Vine DF, Russell JC, Field CJ and Proctor SD. Poster Abstract: Chronic effects of n-3 polyunsaturated fatty acid (PUFA) supplementation on lipid profile, insulin-sensitivity and weight reduction in the JCR:LA-cp rodent during high cholesterol feeding. Alberta Diabetes Institute Retreat, Edmonton, Alberta, September 2006.
  • Lu J, Vine DF, Russell JC, Field CJ and Proctor SD. Poster Abstract: Chronic effects of n-3 polyunsaturated fatty acid (PUFA) supplementation on postprandial lipoprotein metabolism profile in the JCR:LA-cp rodent. Canadian Lipoprotein Conference, Gimli, Manitoba, Canada, September 2006.
  • Hassanali Z, Ruth MR, Gerdung CA, Goruk S, Lu J, MacNaughton K, Sokolik S, Russell JC, Vine DF, Ametaj B, Field CJ and Proctor SD. Acute n-3 PUFA supplementation in the JCR:LA-cp rodent model of insulin-resistance: Effects on post-prandial lipid metabolism and associated inflammatory response. Abstract in Biochemical Society Focused Meeting. Diet and cardiovascular health: Chylomicron remnants and their emerging roles in vascular dysfunction in atherogenesis. December 2006. (Online Pub.)
  • Shi D, Russell JC, Proctor SD and Vine DF. Early cardiovascular disease risk factors in an obese rodent model of polycystic ovarian syndrome. Canadian Obesity Network, Western Obesity Summit, Kananaskis, Canada, May 2007.
  • Lu J, Vine DF, Ruth MR, Glimm DR, Silva E, Field CJ and Proctor SD. Long term effects of dietary CLA:c-9,t-11-enriched butter oil and n-3 polyunsaturated fatty acids (PUFA) on dyslipidemia, obesity and insulin resistance in the JCR:LA-cp rodent. CLA Network Meeting, Kananaskis, Canada, May 2007.
  • Wang Y, Lu J, Gerdung CA, Vine DF, Field CJ and Proctor SD. Beneficial lipid lowering effects of acute transvaccenic acid supplementation in the animal model of obesity and insulin-resistance JCR: LA-cp rat. CLA Network Meeting, Kananaskis, Canada, May 2007.
  • Lu J, Vine DF, Ruth M, Glimm DR, Silva E, Field CJ and Proctor SD. Chronic effects of CLA:c-9,t-11-enriched butter oil and n-3 PUFA supplementation on dyslipidemia and renal pathophysiology in a obese rodent model. Canadian Nutrition Conference, Winnipeg, Canada, June
  • Wang Y, Lu J, Gerdung CA, Vine DF, Field CJ and Proctor SD. Acute supplementation of transvaccenic acid improves plasma lipid profiles in the obese and insulin resistant JCR: LA-cp rat. Canadian Nutrition Conference, Winnipeg, Canada, June 2007.
  • Lu J, Vine DF, Ruth M, Glimm DR, Silva E, Field CJ and Proctor SD. Chronic effects of CLA:c-9,t-11-enriched butter oil and n-3 polyunsaturated fatty acids (PUFA) supplementation in a rodent of obesity and insulin resistance: Effects on dyslipidemia and renal pathophysiology. CLA Workshop AFMNet, Winnipeg, Canada, June 2007.
  • Hassanali Z, England A, O’Neill D, MacNaughton K, Vine DF, Cheeseman C and Proctor SD. Characterization of intestinal villus morphology and corresponding chylomicron production in the JCR:LA-cp rodent, a model of the metabolic syndrome and post-prandial dyslipidemia. Canadian Lipoprotein Conference Quebec, Oct. 2007.
  • Proctor SD, Kelly S, Vine DF and Lopaschuk GD. Echo-cardiographical effect of apoAI infusions in the hyper-insulinemic JCR:LA-cp rat, a spontaneous model of left ventricular dysfunction. Canadian Lipoprotein Conference Quebec, Oct. 2007.
  • Proctor SD, Kelly S, Vine DF and Lopaschuk GD. Echo-cardiographical effect of apoAI infusions in the hyper-insulinemic JCR:LA-cp rat, a spontaneous model of left ventricular dysfunction. Canadian Lipoprotein Conference Quebec, Oct. 2007.
  • Shi D, Russell JC, Proctor SD and Vine DF. Intestinal Chylomicronemia and Postprandial Dyslipidemia and in a Rodent Model of both Polycystic Ovarian and the Metabolic Syndrome. Canadian Lipoprotein Conference Quebec, Oct. 2007.
  • Proctor SD, Kelly S, Vine DF and Lopaschuk GD. Acute echo-cardiographical effect of APO-AI infusion in an animal model of left ventricular dysfunction and insulin resistance. International Atherosclerosis Society Workshop on HDL, Greece October 2007.
  • Shi D, Russell JC, Proctor SD and Vine DF. Postprandial Dyslipidemia and Insulin-Resistance in a Rodent Model of the Polycystic Ovarian Syndrome. Canadian Diabetes Association, Vancouver, Oct. 2007.
  • Hassanali Z, England A, O’Neill D, Vine DF, Cheeseman C and Proctor SD. Intestinal villi hypertrophy is associated with over-production of intestinal chylomicrons during conditions of obesity and hyperinsulinemia in the JCR:LA-cp rodent. International Society for Chylomicrons in Disease, Lake Louise, March 2008.
  • Shi D, Russell JC, Proctor SD and Vine DF. Intestinal Chylomicronemia and Post-prandial Dyslipidemia in a Rodent Model of Polycystic Ovary Syndrome. Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl.
  • Vine DF, Kelly SE, MacNaughton K, Hassanali Z, Mangat R, Madsen K and Proctor SD. Exacerbated Production of Intestinal Lymph Chylomicrons is Associated with Increased Intestinal Transport of Cholesterol Curing Hyper-Insulinemia in the JCR:LA—cp Rodent. Proceedings of International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl.
  • Wang Y, Lu J, Ruth MR, MacNaughton K, Kelly SE, Shi D, Goruk SD, Glimm D, Reaney MJ, Vine DF, Field CJ and Proctor SD. Novel Hypolipidemic Properties of Trans-11 Vaccenic Acid is Partially due to Reduced Chylomicron Production and Improved Post-Prandial Lipemia in the JCR:LA—cp Rat. International Symposium of Chylomicrons in Disease, Lake Louise, Canada March 2008 Athero. Suppl.
  • Field, CJ, Hosea H, Wang Y, Vine D, Proctor SD. Evidence for beneficial effects of the trans fat, vaccenic acid, on health. Canadian Society Clinical Nutrition, Toronto Canada, May 2008.
  • Wang Y, Jacome-Sosa M, Lu J, Ruth MR, Goruk SD, Glimm D, Reaney MJ, Wright DC, Vine DF, Field CJ and Proctor SD. Newly described hypolipidemic benefits of trans-11 vaccenic acid in a rodent model of dyslipidemia and the metabolic syndrome. 29th Western Nutrition Conference, Edmonton Canada, September 2008 and World Dairy Congress, Mexico City, November 2008.
  • Jacome-Sosa M, Wang Y, Lu J, Ruth M, Goruk S, Reaney MJ, Glimm DR, Vine DF, Field CJ, Silva-Hernandez ER, Proctor SD. Hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid (CLA) alone or in combination with trans-11 vaccenic acid (VA) in a rodent model of dyslipidemia and the metabolic syndrome. 29th Western Nutrition Conference and Alberta Diabetes Institute Annual Research Day Edmonton Canada, September 2008 and World Dairy Congress, Mexico City, November 2008
  • Proctor SD, Russell JC and Vine DF. Characterization of a novel rat model of intestinal lipoprotein over production in obesity and insulin resistance.  National Atherosclerosis Forum. Pfizer Canada Inc. Toronto, Canada, September 2008.
  • Proctor SD, Russell JC and Vine DF. Overproduction of Intestinal lymph chylomicrons is associated with hyperinsulinemia in the JCR:LA-cp rodent model of the metabolic syndrome. CSATVB, Toronto, Canada, October 2008.  
  • Wang Y, Jacome-Sosa M, Lu J, Ruth MR, Goruk SD, Glimm D, Reaney MJ, Wright DC, Vine DF, Field CJ and Proctor SD. Newly described hypolipidemic benefits of trans-11 vaccenic acid in a rodent model of dyslipidemia and the metabolic syndrome. Canadian Lipoprotein Conference, Whistler, Canada, October 2008.
  • Warnakula S, Mangat R, .Wang Y, Uwiera RR, MacNaughton K, Jakhura A, Russell JC, F. Vine and Proctor SD.  Effect of Ezetimibe and Simvastatin on Intestinal Lymphatic Chylomicron Over-Production in the Hyperinsulinemic JCR:LA-CP Rat.  Canadian Lipoprotein Conference, Whistler, Canada, October 2008.
  • Uwiera RR, Shi D, and Vine. Polycystic ovaries in JCR:LA-cp/cp rats.  Western Conference of Diagnostic Pathologists.  Saskatoon Canada, October 2008.
  • Jacome-Sosa M, Wang Y, Lu J, Ruth M, Goruk S, Reaney MJ, Glimm DR, Vine DF, Field CJ, Silva-Hernandez ER, Proctor SD. Hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid (CLA) alone or in combination with trans-11 vaccenic acid (VA) in a rodent model of dyslipidemia and the metabolic syndrome. Abstract in Proceedings in the Canadian Lipoprotein Conference, Whistler, Canada, October 2008.
  • Shi D, Jakhura A, Uwiera RR, Dyck M, Russell JC, Proctor SD and Vine DF. Polycystic ovary and metabolic syndrome:  Establish of the JCR:LA-cp rodent model.  Poster in WCHRI Research Day 2008, Edmonton, Canada, November 2008.
  • Mangat R, Wang Y, Warnakula S, Uwiera RR, Vine DF and Proctor SD. Increased retention of intestinally derived chylomicron-remnants in arteries of JCR:LA-cp insulin-resistant rats ex-vivo is associated with binding to biglycan: Potential of vascular remodeling in accelerated cardiovascular disease during diabetes. Vascular Matrix Biology and Bioengineering workshop presented by the North American Vascular Biology Organization. Whistler, British Columbia. March 2009.
  • Vine DF, Hassanali Z, Mangat R, Wang Y, Uwiera RR, Russell JC, Proctor SD.  Exacerbated production of intestinal lymph chylomicrons is associated with increased transport of cholesterol and intestinal hypertrophy in the pre-diabetic JCR:LA-CP Rat.  Abstract in Proceedings of 3rd International Congress on pre-diabetes and the Metabolic Syndrome. Nice, France, April 2009.
  • Vine DF, Shi D, Jakhura A, Uwiera RR, Dyck M, Proctor SD, Russell JC.  Dyslipidemia in a rodent model of the metabolic and polycystic ovary syndrome.  3rd International Congress on Prediabetes and the Metabolic Syndrome, France, April 2009.
  • Jacome-Sosa MM, Wang Y, Lu J, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Vine DF, R. Silva-Hernandez, C.J. Field and S.D. Proctor. c-9, t-11 conjugated linoleic acid alone or in combination with t-11 vaccenic acid improves dyslipidemia and hepatic steatosis in a rodent model of the metabolic syndrome. Abstract in Proceedings of the Canadian Society for Clinical Nutrition’s 8th Annual Scientific Meeting.  Quebec City, Canada.  May 2009.
  • Ruth MR, Wang Y, Yu HM, Proctor SD,  Vine DF, and Field CJ.  The effects of vaccenic acid and elaidic acid on immune function in a rodent model of obesity and insulin resistance.  Abstract in Proceedings of the Canadian Society for Clinical Nutrition’s 8th Annual Scientific Meeting.  Quebec City, Canada.  May 2009.
  • Jacome-Sosa MM, Wang Y, Lu J, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Vine DF, Silva-Hernandez ER, Field CJ and S.D. Proctor. c-9, t-11 conjugated linoleic acid alone or in combination with t-11 vaccenic acid improve dyslipidemia and hepatic steatosis in a rodent model of the metabolic syndrome. Abstract accepted, Canadian Society for Clinical Nutrition, Montreal, Canada May 2009.
  • Wang Y, Jacome-Sosa MM, Ruth R, Goruk SD, Reaney MJ, Glimm DR, Wright DC, Vine DF, Field CJ and Proctor SD. Novel hypolipidemic benefits of trans-11 vaccenic acid are partially contributed by reduced hepatic lipogenesis and lower intestinal chylomicron secretion in the JCR:LA-cp rat. Abstract accepted, Canadian Society for Clinical Nutrition, Montreal, Canada May 2009.
  • Wang Y, Jacome-Sosa MM, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Wright DC, Vine DF, Field C, and Proctor SD. Novel hypolipidemic benefits of trans-11 vaccenic acid are partially contributed by reduced hepatic lipogenesis and lower intestinal chylomicron secretion in the JCR:LA-cp rat.  Quebec City, Canada.  May 2009.
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Trans-11 vaccenic acid bioavailability from different food sources and effects on intestinal chylomicron production in the JCR:LA-cp rodent model”.  Abstract in proceedings of the Canadian Lipoprotein Conference in Windsor, Canada, October 2009.
  • Field CJ, Ruth MR, Yu H, Wang Y, Proctor SD, and Vine DF. The beneficial effect of feeding a trans fatty acid, vaccenic acid, on immune function in a rodent model of obesity and insulin resistance. Abstract in Proceedings of International Diabetes Federation in Montreal, Canada, October. 2009.
  • Mangat R, Vine DF, Forbes JM, Cooper ME, Mamo JCL and Proctor SD. Arterial retention of remnant lipoproteins is decreased by a combination of ezetimibe and simvastatin in insulin resistant JCR-LA-cp rats. Abstract in Proceedings of the Canadian Society of Atherosclerosis Thrombosis and Vascular Biology in Edmonton, Canada, October 2009.
  • Jakhura A, Ball G, Jetha M, Proctor SD, and Vine DF. Polycystic Ovary Syndrome: The assessment of Risk Factors for Type-2 Diabetes and Cardiovascular Disease in Obese Adolescent Girls. Alberta Institute for Human Nutrition: Seminar series, Edmonton, October 2009.  
  • Jakhura A, Ball G, Jetha M, Proctor SD, and Vine DF. The pathophysiology and assessment of risk factors for Type 2 diabetes and cardiovascular disease in a clinical investigation in overweight adolescent girls. Women and Children’s Health Research Institute Conference, Edmonton, November 2009.
  • Warnakula S, Mangat R,  Wang Y,  MacNaughton K, Russell JC, Uwiera RR, Vine DF, and Proctor SD.  Combination therapy of ezetimibe and simvastatin ameliorates myocardial lesion frequency and synergistically reduces arterial retention of remnant lipoproteins in insulin-resistant JCR:LA-CP rats.  Abstract in proceedings of Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions in San Francisco, USA, April 2010.
  • Pendlebury C, Nzekwu M, Vine DF, .Beaulieu C, Jetha MM, Ball G, Proctor SD. Elevated chylomicron concentrations in obese pre-pubertal children may be an early marker of cardiovascular disease risk.  Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010.
  • Jacome-Sosa MM, Wang Y,  Lu J, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Vine DF, Silva-Hernandez ER, Field CJ and. Proctor SD. Synergistic effects of natural trans-fats, cis-9, trans-11 conjugated linoleic acid (CLA) and trans-11 vaccenic acid in the JCR:LA-cp rat.  Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010.
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Trans-11 vaccenic acid is bioavailable from different food sources and reduces intestinal chylomicron secretion in the JCR:LA-CP rat model. Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010.
  • Borthwick F, Lu J, Hassanali Z, Wang Y, Mangat R, Ruth M, Shi D, Russell JC, Field CJ, Jaeschke A*, Vine DF and Proctor SD . Dietary N-3 PUFA improves post-prandial metabolism in the insulin resistant JCR:LA-CP rat by lowering enterocytic APO-B48 production and lymphatic cholesterol. Abstract in proceedings of 9th Conference of the International Society for the Study of Fatty Acids and Lipids in Maastricht, The Netherlands. May 2010.
  • Mangat R, Vine DF, Forbes JM, Cooper ME, Mamo JCL and Proctor SD. Increased risk of cardiovascular disease in type 1 diabetes: Increased arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans. Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010.
  • Wang Y, Jacome-Sosa M.M, MacNaughton K, Field CJ, Proctor SD, Vine DF. Dietary Trans-11 Vaccenic Acid Increases Intestinal PPAR Alpha and Gamma Expression in the JCR:LA-cp Rat. Abstract in proceedings of International Symposium on Chylomicrons in Disease-2 (ICSD) Rotterdam, Netherlands, June 2010. Merck-Schering, ALIDF.
  • Rodríguez Dimitrescu A., Proctor, R. Jacobs, D. Vine. Lipid metabolism in the JCR:LA rodent model of polycystic ovary syndrome.  Effects of flutamide and metformin.  Abstract in proceedings of Canadian Lipoprotein Conference, Niagara on the Lake, Canada. October 2010.
  • Borthwick F, Mangat R, Uwiera RE, Vine DF, Proctor SD. The retention (ex-vivo) of both intestinal and hepatically-derived remnant lipoproteins is increased in arterial vessels from insulin resistant JCR:LA-cp rats, but efflux (removal) is differential. Abstract in proceedings of Canadian Lipoprotein Conference, Niagara on the Lake, Canada. October 2010  
  • Pendlebury C, Ball G, Jetha M, Proctor S and Vine D. Dyslipidemia in obesity and polycystic ovary syndrome. Abstract in proceedings of Alberta Diabetes Institute Research Day.  Edmonton, Canada, October 2010.
  • Rodríguez Dimitrescu A., S. Proctor, R. Jacobs, Vine. Effects of Flutamide and Metformin on lipid metabolism in a rodent model. Abstract in proceedings of Alberta Diabetes Institute Research Day.  Edmonton, Canada, October 2010.
  • Jacome-Sosa M., Y. Wang, J. Lu, M.R. Ruth, S.D. Goruk, M.J. Reaney, D.R. Glimm, F. Vine, Trans-11 vaccenic acid increases energy expenditure, lowers total body fat as well as changes fat distribution after feeding high saturated fat diet in a rat model of the metabolic syndrome, the JCR:LA-cp rat.  AFNS 601 Seminar Series.  Edmonton, Canada, October 2010.
  • Rodríguez Dimitrescu A, Proctor SD, Jacobs R, Vine. Lipid metabolism in the JCR:LA rodent model of polycystic ovary syndrome.  AFNS 601 Seminar Series.  Edmonton, Canada, November 2010.  Role: PI and work of graduate student.
  • Pendlebury C, Ball G, Jetha M,  Proctor SD, and Vine.  Atherogenic Risk Factors in Adolescent Girls: The Influence of Polycystic Ovary Syndrome and Obesity. WCHRI Research Day.  Edmonton, Canada. November 2010.
  • Mangat R, Warnakula S, Borthwick F, Uwiera RR, Russell JC, Vine DF and Proctor SD. Both arterial retention and vascular efflux of remnant lipoprotein cholesterol contribute to CVD risk during insulin resistance in a rodent model of the metabolic syndrome, the JCR:LA-cp rat. Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions in Chicago, USA, April 2011.
  • Hosseini A., T. Lam, U. Farooq, S. M. Dunn, Vine DF. Daude, D. Westaway, D. S. Wishart, and B. N. Ametaj. Lipopolysacharide affects permeation of prion protein through the gastrointestinal tract of rodents. PRION Conference, Montreal, Quebec, May 2011.
  • Rodríguez Dimitrescu P, Vine DF, Yap J, Mazurak M. Gilmour S. Mager D. Effect of saturated fat on postprandial lipid and lipoprotein metabolism in children with nonalcoholic fatty liver disease (NAFLD). Canadian Nutrition Society, Guelph, Canada, June 2011.
  • Borthwick F, Mangat R. Vine DF, Proctor SD. Statin treatment upregulates intestinal lipid secretion pathways in the insulin resistant JCR:LA-cp rat. Cardiac Sciences Research Day 2011. Edmonton, Canada.  June 2011.  
  • Jacome-Sosa M, Reaney MJ, Shen J, Field CJ, Vine DF and Proctor SD..  Bioactivity of natural versus synthetic trans vaccenic acid in the JCR:LA-CP  24th Canadian Conference on Fats and Oils, Edmonton, Canada September 2011.
  • Wang Y, Jacome-Sosa MM, Ruth MR, Reaney MJ, Shen J, Field CJ, Vine DF. and S.D Proctor.  Ruminant trans fat trans-11 vaccenic acid is a natural peroxisome proliferator-activated receptor ligand and synergistically improves dyslipidemia with dietary conjugated linoleic acid.  24th Canadian Conference on Fats and Oils, Edmonton, Canada September 2011.
  • Aziz NA, Kelly KB, Légaré M, Leonard KA, Dellschaft N, Goruk S, Curtis J, Vine DF.  Spencer Proctor, Catherine Field, René L. Jacobs. Does Phosphatidylcholine Supply Modulate Intestinal Lipoprotein Metabolism?  24th Canadian Conference on Fats and Oils, Edmonton, Canada September 2011
  • Pendlebury C, Ball G, Jetha M, Vine DF. Polycystic Ovary Syndrome: Early Indicators of Atherogenic Dyslipidemia in Obese Adolescent Girls. Canadian Diabetes Association and Canadian Society Endocrinology and Metabolism Annual Meeting. Toronto, Canada. October 2011.
  • Rodríguez Dimitrescu A, Proctor SD, Jacobs R, Vine DF. Polycystic Ovary Syndrome: Exploring Mechanisms of Atherogenic Dyslipidemia in a Rodent Model.  Canadian Diabetes Association and Canadian Society Endocrinology and Metabolism. Toronto, Canada. October 2011.
  • Borthwick F, Jacome-Sosa MM, Nelson R, Jacobs R, Vine DF and Proctor SD. High-throughput mRNA analysis of lipogenic genes (hepatic and intestinal) regulated during insulin resistance in the JCR:LA-CP Rat.  Alberta Diabetes Institute Research Day, Edmonton, Canada, October 2011.
  • Mangat R, Borthwick F, Uwiera RR, Russell JC, Vine DF and Proctor SD. Remodelling of the vessel wall during insulin resistance may explain preferential retention of cholesterol-rich remnant lipoproteins and increased CVD in the JCR:LA-CP rat. Alberta Diabetes Institute Research Day, Edmonton, Canada, October 2011.
  • Wang Y, Jacome-Sosa MM, Reaney MJ, Shen J, Scott S, Field CJ, Vine DF and Proctor SD. Ruminant trans fat trans-11 vaccenic acid is more bioavailable from a triglyceride source and regulates intestinal lipid metabolism via peroxisome proliferator activated receptor-dependent pathways in a rodent model of dyslipidemia and metabolic syndrome. Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Borthwick F, Mangat R, Vine DF, Proctor SD. Statin treatment upregulates intestinal lipid secretion pathways in the dyslipidemic, insulin resistant JCR:LA-cp Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Mangat R, Borthwick F, Uwiera RR, Russell JC, Vine DF, Proctor S.  Remodeling of the vessel wall during insulin resistance may explain preferential retention of cholesterol-rich remnant lipoproteins and increased CVD in the JCR:LA-cp rat. Canadian Lipoprotein Conference.  Halifax, Canada. November 2011.
  • Rodríguez Dimitrescu A, Proctor SD, Jacobs R, Vine DF. Understanding mechanisms of atherogenic dyslipidemia in a rodent model of polycystic ovary syndrome. Women and Children’s Health Research Institute Research Day, Edmonton, Alberta, November 30th, 2011.
  • Wang Y, Ball G, Jetha M. Vine DF. Postpranidal dyslipidemia in adolescents with polycystic ovary syndrome: evidence of early cardiovascular risk. Women and Children’s Health Research Institute Research Day, Edmonton, Alberta, November 30th, 2011
  • Rodríguez Dimitrescu A, Vine DF, Yap J, Mazurak M. Gilmour S. Mager D. Acute intake of saturated fat/polyunsaturated fat influences postprandial lipid and lipoprotein metabolism in children with nonalcoholic fatty liver disease (NAFLD). American Society for Parenteral and Enteral Nutrition, Clinical Nutrition Week.  Orlando, USA.   January 2012.
  • Borthwick F, Mangat R, Vine DF, Proctor SD. Statin treatment upregulates intestinal lipid secretion pathways in a rodent model of insulin resistant and CVD, the JCR:LA-cp rat. International Symposium on Atherosclerosis Conference.  Sydney, Australia.  March 2012.
  • Mangat R, Borthwick F, Uwiera RR, Vine D, Proctor SD. Remodeling of the vessel wall during insulin resistance may explain preferential retention of cholesterol-rich remnant lipoproteins and increased CVD in the JCR:LA-cp rat. International Symposium on Atherosclerosis Conference.  Sydney, Australia.  March 2012.
  • Wang Y, Jacome-Sosa MM, Ruth MR, Reaney MJ, Shen J, Field CJ, Vine DF, Proctor SD. Dairy trans-fat, trans-11 vaccenic acid, is a natural nuclear receptor (PPAR) ligand and synergistically improves dyslipidemia in combination with conjugated linoleic acid in the diet.  Therapeutic Applications of Functional Foods Conference. Winnipeg, MB. May 2012.
  • Wang Y, Jacome-Sosa MM, Reaney MJ, Shen J, Scott S, Anderson H, Field CJ, Vine DF and Proctor SD. Ruminant trans-11 vaccenic acid activates peroxisome proliferator-activated receptor-dependent pathways and improves cardiomyocyte hypertrophy associated with the metabolic syndrome. International Society for the Study of Fatty Acids and Lipids. Vancouver, Canada.  May 2012.
  • Wang F, Jetha M, Ball GD, Proctor SD, Vine DF. Atherogenic Dyslipidemia in Obese Adolescents and a Rodent Model of Polycystic Ovary Syndrome. Endocrinology, Houston, Texas, June 2012.
  • Baillargeon JP, Vine DF, Battista MP. Role of non-esterified fatty acid in the hyperandrogenemia of a rat model of PCOS.  Androgen Excess and Polycystic Ovary Society, Houston, Texas, June 2012.
  • Borthwick F, Ullrich T, Mangat R, Jacome-Sosa MM, Kelly SE, Proctor SD, Vine DF. Niacin increases the secretion of intestinal derived lipid-poor HDL particles in a rat model of insulin resistance. Frontiers in Lipid Biology, Am Soc Biochem and Molec Biol, Canadian Lipoprotein Conference.  Banff, Canada.  September 2012.
  • Mangat R, Ullrich T, Borthwick F, Jacome M, Kelly SE, Proctor SD, Vine DF. Niacin attenuates intestinal chylomicron over-secretion in the JCR:LA-cp rat: a model of metabolic syndrome and insulin resistance.  Frontiers in Lipid Biology, Am Soc Biochem and Molec Biol, Canadian Lipoprotein Conference.  Banff, Canada.  September 2012.
  • Wu S, Borthwick F, Mangat R, Vine DF, Proctor SD. Over-secretion of intestinal apoB48 lipoproteins is associated with decreased enterocytic heat shock protein-90 in a rat model of insulin-resistance. Frontiers in Lipid Biology, Am Soc Biochem and Molec Biol, Canadian Lipoprotein Conference.  Banff, Canada.  September 2012.
  • Wang Y, Diané A, Kelly SE, Jacobs RL, Proctor SD, Vine DF. Metformin and flutamide attenuate plasma and lymphatic apoB48 and apoB100 concentrations in the JCR:LA-cp rat: a model of insulin resistance and polycystic ovary syndrome.  Frontiers in Lipid Biology, Am Soc Biochem and Molec Biol, Canadian Lipoprotein Conference.   Banff, Canada.  September 2012.
  • Ullrich T, Borthwick F, Mangat R, Jacome M, Kelly SE, Proctor SD, Vine DF. Niacin increases the secretion of intestinal derived lipid poor HDL particles in a rat model of insulin resistance. Frontiers in Lipid Biology, Am Soc Biochem and Molec Biol, Canadian Lipoprotein Conference, Banff, Canada, September 2012.
  • Mangat R, Ullrich T, Borthwick F, Jacome M, Kelly SE, Proctor SD, Vine DF. Niacin attenuates intestinal chylomicron over-secretion in the JCR:LA-cp RAT:  A model of metabolic syndrome and insulin resistance.  ADI Research Day, September 2012.
  • Castro GSF, Rajabi A, Da Silva R, Nelson R, Kelly SE, Vine DF, Proctor SD, Jacobs RL. Deleting phosphatidylethanolamine methyltransferase increases dietary choline requirement in the LDLR-/- mice.  AIHN 4th Annual Student/Trainee Poster Competition.  February 2013.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin beneficially alters the secretion of intestinal derived TRL and HDL in a rat model of insulin resistance. Arteriosclerosis, Thrombosis and Vascular Biology 2013 Scientific Sessions.  Florida, USA.  May 2013.
  • Diané Abdoulaye, Pierce W David, Faye Borthwick, Jacob René, Nelson Randal, Heth Donald C, Russell James C, Vine Donna F, Proctor Spencer D. Differential Expression of Hypothalamic Metabolic and Inflammatory Genes in Response to Short-Term Calorie Restriction in Young Obese- and Lean-prone JCR Rats. 3rd Canadian Obesity Summit.  Vancouver, Canada.  May 2013.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin beneficially alters the secretion of intestinal derived triglyceride rich lipoprotein and HDL in a rat model of insulin resistance.  Mazankowski Cardiac Sciences Research Day.  June 2013.
  • Borthwick F, Mangat R, Warnakula S, Jacome M, Vine DF, Proctor SD. Simvastatin treatment upregulates intestinal lipid secretion pathways in a rodent model of the metabolic syndrome.  Mazankowski Cardiac Sciences Research Day. June 2013.
  • Kupreeva M, Wang F, Diane A, Kelly SE, Ghosh M, Jacobs RL, Proctor SD, Vine DF. Lipid metabolism in prediabetes and polycystic Ovary Syndrome:  Investigating the modulatory role of testosterone and insulin in a rodent model. Mazankowski Cardiac Sciences Research Day.  Edmonton, Canada.  June 2013.
  • Ala Al Rajabi, Nicole Coursen, Kelly-Ann Leonard, Sandra Kelly, Donna Vine, Spencer Proctor and René Jacobs. Choline status modulates the development of atherosclerosis in Ldlr-/- Mazankowski Cardiac Sciences Research Day.  Edmonton, Canada.  June 2013.
  • Leblanc S, Battista MC, Gallo-Payet N, Vine DF, Carpentier AC, Baillargeon JP. Role of Non-Esterified Fatty Acid in the Hyperandrogenemia of a Rat Model of Polycystic Ovary Syndrome. Endocrine Society.  San Francisco, USA.  June 2013.
  • Kupreeva M, Wang Y, Diane A, Kelly SE, Ghosh M, Jacobs RD, Proctor SD, Vine Targeting testosterone and insulin to determine effects on lipid metabolism in a rodent model of prediabetes and polycystic ovary syndrome.  Alberta Diabetes Institute Research Day. September 2013
  • Rajabi A, Da Silva R, Nelson R, Kelly SE, Vine DF, Proctor SD, Jacobs RL. Choline status modulates the development of atherosclerosis in Ldlr-/- mice.  Canadian Lipoprotein Conference.  Mont Tremblant, Canada.  September 2013
  • Jacome MM, Mangat R, Reaney MJ, Vine DF, Banni S, Proctor SD. Beneficial tissue specific regulation of endocannabinoids by vaccenic acid during insulin resistance.  Canadian Lipoprotein Conference.  Mont Tremblant, Canada.  September 2013
  • Faye Borthwick, Rabban Mangat, Samantha Warnakula, Miriam Jacome, Donna F Vine, Spencer D Proctor. Simvastatin treatment results in a compensatory upregulation of lipid secretion by the intestine in a rodent model of the metabolic syndrome. Canadian Lipoprotein Conference.  Mont Tremblant, Quebec.  September 2013.
  • Wang F, Jetha M, Ball G, Proctor S, Vine DF. Atherogenic dyslipidemia in adolescents with polycystic ovary syndrome.  Molecular Cell Biology of Lipids Research Day.  Edmonton, Canada.  September 2013.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin simultaneously benefits the secretion of both intestinal chylomicrons and HDL in a rat model of insulin resistance by stimulating the PPAR alpha pathway in enterocytes.  Canadian Lipoprotein Conference.  Mont Tremblant, Quebec.  September 2013.
  • Diane A, Kupreeva M, Pierce D, Kelly S, Proctor SD, Vine DF. Lifestyle and Pharmaceutical Combination Therapy on Cardiometabolic Risk and Reproductive Indices in a Rodent Model of Prediabetes and Polycystic Ovary Syndrome. Canadian Diabetes Association, Canadian Society Endocrinology & Metabolism. Montreal, Canada.  October 2013.
  • Kupreeva M, Wang F, Diane A, Kelly SE, Ghosh M, Jacobs RL, Proctor SD, Vine DF. Differentiating the Role of Testosterone and Insulin Mediated Effects on Lipid Metabolism in a Rodent Model of Prediabetes and Polycystic Ovary Syndrome. Canadian Diabetes Association, Canadian Society Endocrinology & Metabolism. Montreal, Canada.  October 2013.
  • Wang F, Jetha M, Ball G, Proctor S, Vine DF. Atherogenic dyslipidemia in adolescents with polycystic ovary syndrome.  Molecular Cell Biology of Lipids Research Day.  Edmonton, Canada.  October 2013.
  • Borthwick F, Mangat R, Warnaula S, Jacome M, Vine DF, Proctor SD. Simvastatin and ezetimibe have opposing regulation on intestinal cholesterol absorption and trans intestinal cholesterol excretion (TICE) during metabolic syndrome.  82nd European Atherosclerosis Society Congress.  Madrid, Spain.  May 2014.
  • Mangat R, Borthwick F, Jacome M, Vine DF, Voroz S, Proctor SD. Reduced ‘egress’ of remnant lipoproteins from arterial tissue relative to LDL during insulin resistance may explain a preferential role in atherosclerosis progression.  Arteriosclerosis, Thrombosis and Vascular Biology.  Toronto, Canada.  May 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin beneficially alters the secretion of intestinal HDL in a rat model of insulin resistance by opposing effects on PPAR alpha and TNF alpha.  Arteriosclerosis, Thrombosis and Vascular Biology-Scientific Sessions.  Toronto, Canada.  May 2014.
  • David W. Lim, Crystal Levesque, Paul W. Wales, Donna Vine, Faye Borthwick, Patrick Nation, Pamela Wizzard, Jessica Josephson, David Sigalet, David Bigam, Julang Li, Justine M. Turner. Alterations in intestinal morphology, histology and permeability with exogenous glucagon-like peptide 2 and epidermal growth factor treatment promote intestinal adaptation in neonatal intestinal failure.  Experimental Biology.  San Diego, USA.  April 2014
  • Lim DW, Turner JM, Vine DF, Nation PN, Wizzard PR, Bigam DL, Sigalet DL, Wales PW. Combined Glucagon-like Peptide-2 and Epidermal Growth Factor Therapy Maximally Stimulates Adaptation in Neonatal Intestinal Failure without ileum.  Environmental Biology.  San Diego, USA.  April 2014.
  • Lim DW, Turner JM, Vine DF, Nation PN, Wizzard PR, Bigam DL, Sigalet DL, Wales PW. Combined Glucagon-like Peptide-2 and Epidermal Growth Factor Therapy Maximally Stimulates Adaptation in Neonatal Intestinal Failure without ileum.  Environmental Biology.  San Diego, USA.  November 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated microRNA Profile in Rat Model of Insulin Resistance.  Canadian Nutrition Society, St. Johns, Canada June 2014.
  • David W. Lim, Crystal Levesque, Paul W. Wales, Donna Vine, Faye Borthwick, Patrick Nation, Pamela Wizzard, David Sigalet, David Bigam, Justine M. Turner. Exogenous glucagon-like peptide 2 therapy in a piglet model of neonatal short bowel syndrome promotes intestinal adaptation.  Digestive Disease Week.  Edmonton, Canada.  June 2014.
  • David W. Lim, Crystal Levesque, Paul W. Wales, Donna Vine, Faye Borthwick, Patrick Nation, Pamela Wizzard, David Sigalet, David Bigam, Justine M. Turner. Exogenous glucagon-like peptide 2 therapy in a piglet model of neonatal short bowel syndrome promotes intestinal adaptation.  American Pediatric Surgical Association.  Boston, USA.   June 2014.
  • Mangat R, Borthwick F, Ullrich T, Nelson R, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated microRNA Profile in a Rat Model of Insulin Resistance.  FASEB Journal.  Federation of American Societies for Experimental Biology (FASEB).  Molecular Mechanisms of Intestinal Lipid Transport and Mechanism.  Keystone, USA.  July 2014.
  • G, Proctor. S, Ghosh. M, Jacobs. R, & Vine. DF. Testosterone modulation of lipid metabolism in pre-diabetes and polycystic ovary syndrome. Alberta Mazankowski Heart Institute, Cardiac Sciences Research Day.    Edmonton, Canada.  June 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated Mirna Profile in a Rat Model of Insulin Resistance.  Alberta Mazankowski Heart Institute, Cardiac Sciences Research Day. Edmonton, Canada.  June 2014.
  • Mangat R, Borthwick F, Warnakula S, Jacome-Sosa MM,  Vine D, Proctor SD.  Simvastatin and ezetimibe have opposing regulation on intestinal cholesterol absorption and trans intestinal cholesterol excretion (tice) during metabolic syndrome.  American Heart Association Scientific Session. Published in Atherosclerosis Journal 2014 Aug; 235(2):e185.
  • Mangat R, Warnakula S, Borthwick F, Vine DF, Proctor SD. Simvastatin and Ezetimibe are opposing in their Regulation of Intestinal Cholesterol Absorption and Trans Intestinal Cholesterol Excretion (TICE) in a Rodent Model of the Metabolic Syndrome.  Canadian Lipoprotein Conference.  Saskatoon, Canada.  October 2014.
  • Diane A, Kupreeva M, Jacobs RL, Proctor SD, Vine DF. Androgen and insulin mediated effects on lipid metabolism in a rodent model of polycystic ovary syndrome (PCOS). Canadian Lipoprotein Conference, Saskatoon, Canada. October 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin alters the secretion of intestinal lymphatic HDL and associated miRNA profile in a rat model of insulin resistance.  Canadian Cardiovascular Congress.  Vancouver, Canada.  October 2014.
  • Mangat R, Borthwick F, Ullrich T, Jacome M, Vine DF, Proctor SD. Niacin Alters the Secretion of Intestinal Lymphatic HDL and Associated Mirna Profile in a Rat Model of Insulin Resistance.  ADI Research Day, Alberta Diabetes Institute. Edmonton, Canada. October 2014.
  • Mangat R, Borthwick F, Vine DF, Proctor SD. Lymphatic HDL can act as a donor for TICE and this pathway is impaired under conditions of insulin resistance and high fat diet.  DEUEL Conference. Monterey, USA.  March 2015.
  • Mangat R, Borthwick F, Vine DF, Proctor SD. Lymphatic derived HDL Is An Effective Donor For The Trans-Intestinal Cholesterol Efflux Pathway That Is Impaired During Insulin Resistance.  ATVB 2015.  San Francisco, USA.   May 2015.
  • Krysa J, Proctor SD, Vine DF, Ooi T. The Effect of PCSK9 Loss of Function Variants on the Postprandial Response of TG-rich Remnant Lipoproteins. 19th Annual Mazankowski Cardiac Sciences Research Day. Edmonton, Canada. June 2015. – awarded best clinical research presentation.
  • Ananthakrishnan G, Proctor SD, Ghosh M, Jacobs R, Vine DF. Testosterone modulation of lipid metabolism in pre-diabetes and polycystic ovary 19th Annual Mazankowski Cardiac Sciences Day.  Edmonton, Canada.  June 2015.
  • Ooi TC, Krysa J, Abujrad H, Mayne J, Henry K, Cousins M, Raymond A, Favreau C, Taljaard M, Chretien M, Mbikay M, Proctor S, Vine DF. The Effect of PCSK9 Loss of Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response.  Kern Lipid Conference.  Vail, USA.  August 2015.
  • Anankrishnanthin G, Proctor, SD, Ghosh M, Jacobs R, Vine DF. Androgens differentially modulate triglyceride and cholesterol metabolism in a rodent model of pre-diabetes and poly cystic ovary syndrome.  Alberta Diabetes Institute Research Day. Edmonton, Canada.  October, 2015.
  • Diane A, Mangat R, Kelly SE, Fontaine MA, Singh VP, Li J, Willing B, Vine DF, Proctor SD. Low birth weight leads to increased intestinal lipid absorption during both insulin sensitive and insulin resistant conditions in Landrace pigs.  Alberta Diabetes Institute Research Day. Edmonton, Canada.  October, 2015.
  • Mangat R, Vine DF, Proctor SD. Lymphatic HDL can act as a donor for TICE (Trans-intestinal cholesterol efflux) and this pathway is impaired under conditions of insulin resistance.  Alberta Diabetes Institute Retreat.  Edmonton, Canada.  October 2015
  • Ooi TC, Krysa J, Abujrad H, Mayne J, Henry K, Cousins M, Raymond A, Favreau C, Taljaard M, Chretien M, Mbikay M, Proctor S, Vine DF. The Effect of PCSK9 Loss of Function Variants on the Postprandial lipid and ApoB-Lipoprotein Response.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Mangat R, Nelson R, Vine DF, Proctor SD. Intestinal HDL apoA-I secretion is reduced and associated miRNAs are altered during insulin resistance that is improved by Niacin.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015
  • Lim DW, Wales PW, Vine DF, Nation P, Wizzard P, Sigalet D, Bigam D, Turner JM. Glucagon-like Peptide-2 Therapy Augments Intestinal Adaptation in a Preclinical Model of Neonatal Short Bowel Syndrome with Distal Intestinal Resection.  Clinical Congress, Scientific Forum.  American College of Surgeons (JACS).  Chicago USA.  October 2015.
  • Soto Y. Mangat R, Vine DF, Proctor SD.  Application of a novel anti-proteoglycan antibody to inhibit acute arterial retention of remnant lipoproteins in a rat model of insulin resistance.  Canadian Lipoprotein Conference.  Toronto, Canada.  October 2015.
  • Anankrishnanthin G, Jacobs R, Proctor SD, Vine DF. Testosterone differentially modulates triglyceride and cholesterol metabolism in a rodent model of polycystic ovary syndrome and the metabolic syndrome. World Diabetes Congress. Canadian Society Endocrinology and Metabolism. World Diabetes Congress. Vancouver, Canada, December, 2015.
  • Diane, R. Mangat, SE. Kelly, MA. Fontaine, VP. Singh, J. Li, B. Willing, D. Vine, SD. Proctor. Low birth weight increases intestinal lipid absorption during insulin sensitive and insulin resistant conditions in pigs. World Diabetes Congress, Vancouver, Canada. December, 2015.
  • Diane A, Kupreeva M, Proctor SD, Pierce DW and Vine DF. Exercise and metformin-flutamide therapy improve cardiometabolic and endocrine-reproductive outcomes in a rodent model of PCOS and metabolic syndrome. World Diabetes Congress, Canadian Society of Endocrinology and Metabolism.  Vancouver, Canada, December, 2015.
  • Mangat R, Vine DF, Proctor SD. Trans-intestinal cholesterol efflux is reduced and associated with HDL-C in diabetic and insulin resistant dyslipidemia.  Canadian Society Endocrinology and Metabolism.  World Diabetes Congress.  Vancouver, Canada, December 2015.
  • Ananthakrishnan G, Proctor SD, Ghosh M, Jacobs RL, Vine DF. Androgens Modulate Plasma and Intestinal Triglyceride and Cholesterol Metabolism in a PCOS-Prone Rodent Model. The Endocrine Society’s 98th Annual Meeting & Expo.  Boston USA.  April 2016.
  • Diané A, Kupreeva M, Pierce WD, Kelly S, Proctor SD and Vine DF. Benefits of Early Energy Restriction and Voluntary exercise in an Obese PCOS-Prone Rodent Model.  United Scientific Group, Obesity & Chronic Diseases-2016.  Las Vegas, USA. July 2016.
  • Krysa JA, Vine DF, Beilin LJ, Burrows S, Huang R-C, Mori T, Proctor SD.. The Relationship of Fasting Plasma ApoB48 to Cardiometabolic Risk Factors in Adolescents. School of Medicine and Pharmacology Seminar Series, University of Western Australia, 2016.
  • Lim DW, Levesque C, Vine DF, Muto M, Koepki J, Nation PN, Wizzard PR, Li J, Sigalet DL, Bigam DL, Brubaker PL, Turner JM, Wales PW. Combination trophic peptide therapy for neonatal short bowel syndrome.  CAPS (Canadian Association of Paediatric Surgeons).  Vancouver, Canada, 2016.
  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs R and Vine D. Androgens modulate intestinal absorption and synthesis of lipids contributing to impaired lipid metabolism in a rodent model of Polycystic Ovary Syndrome and Metabolic Syndrome.  The Canadian Society of Endocrinology and Metabolism Conference and Annual Meeting.  Ottawa, Canada.  October 2016
  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs R and Vine D. Androgens modulate lipid metabolism and lipidogenic pathways in a rodent model of metabolic syndrome and polycystic ovary syndrome.  Alberta Diabetes Institute Research Day, 2016.
  • Ananthakrishnan G, Proctor S, Jacobs R and Vine D. Androgens modulate plasma and intestinal triglyceride and cholesterol metabolism in a PCOS-Prone rodent model.  Cardiac Sciences Research Day, 2016.
  • Jacqueline A Krysa, Donna F Vine, Lawrence J Beilin, Sally Burrows, Rae-Chi Huang, Trevor A Mori, Spencer D Proctor. The Relationship of Fasting Plasma ApoB48 to Cardiometabolic Risk Factors in Adolescents. WCHRI Research Day, Edmonton, Canada, 2016.
  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs R and Vine D. Androgens modulate lipid metabolism in a rodent model of metabolic syndrome and polycystic ovary syndrome. WCHRI Research Day, Edmonton, Canada 2016.
  • Proctor S, Ghosh M, Maximova K, Vine DF. Postprandial dyslipidemia in MetS-PCOS women and impact of a high-fat meal test. Androgen Excess and PCOS SocietyMelbourne, Australia.  November 2016
  • Celeste M. Lavallee, Pamela R. Wizzard, Marihan Lansing, Donna F. Vine, Patrick N. Nation, Jason Y. Yap, Benjamin P. Willing, Paul W. Wales, Justine M. Turner. (2017). Surgical Anatomy Does Not Affect the Progression of Intestinal Failure–Associated Liver Disease in Neonatal ASPEN, US. February 2017.
  • Krysa JA, Vine DF, Beilin LJ, Burrows S, Huang R-C, Mori TA, Proctor SD. ApoB48-lipoprotein Remnants are Associated with Increased Cardiometabolic Risk in Adolescents.    Colorado, USA.  July 2017.
  • Ethan Proctor, Mahua Ghosh, Rabban Mangat, Spencer Proctor, Katerina Maximova, Donna Vine. Fish Oil and Metformin to treat dyslipidemia in women with PCOS.  Alberta Diabetes Research Day.  October 2017.
  • Hope Kurylo, Donna Vine. Dietary Assessment of Women with Polycystic Ovarian Syndrome.  Alberta Diabetes Research Day.  October 2017.
  • Vine DF, Kupreeva M and Proctor SD.  Targeting insulin and androgen receptor signaling pathways differentially modulates insulin-glucose, lipid and ApoB-lipoprotein metabolism, and reproductive-endocrine function in a PCOS-Prone Rodent model.  Androgen Excess & PCOS Society 15th Annual Mtg.  San Antonio, USA.  October 2017.
  • De Jong K, Nelson R, Vine D. Cardiac Dysfunction is Associated with the Metabolic Syndrome in a Polycystic Ovary Syndrome-Prone Rodent Model.  Canadian Society for Endocrinology and Metabolism.  Edmonton, Canada.  November 2017.
  • Kyrsa J, Vine D, Proctor S. ApoB-Remnant Dyslipidemia and High-Fat Meal Intolerance Exacerbates Cardiometabolic Risk in Overweight Children. International Atherosclerosis Society, Toronto, Canada, June 2018.
  • Proctor E, Ghosh M, Mangat R, Proctor S, Maximova K, Vine D. Fish oil and metformin impact lipoprotein metabolism in women with PCOS. Alberta Diabetes Institute, Edmonton, Canada, September 2018.
  • Krysa J, Ball G, Vine DF, Proctor S. Fasting Plasma ApoB-Remnant Lipoproteins Can Predict Impaired Non-Fasting Lipid and ApoB-Lipoprotein Metabolism in Healthy-Weight and Overweight Children. Canadian Diabetes and Canadian Society Endocrinology and Metabolism, Halifax, Canada, October 2018.
  • Proctor S, Ghosh M, Maximova K, Vine D. ApoB-remnant lipoproteinemia in the fasted and non-fasted state in obesity, metabolic syndrome and polycystic ovary syndrome – early subclinical cardiovascular disease risk. International Atherosclerosis Society, Toronto, Canada, October, 2018.
  • Tran T, Sobool C, Ghosh M and Vine D. Dietary Assessment of women with Polycystic Ovary Syndrome. Food Matters, Alberta Health Services, Edmonton, Canada, April 2019.
  • Krysa J, Ball G, Vine D, Proctor S. ApoB‐Remnant Dyslipidemia and High‐ Fat Meal Intolerance Enhances Cardiometabolic‐Risk in Overweight‐Obese Children. Cardiac Sciences Research Day, Edmonton, Canada, June 2019.h
  • Seifried B, Temelli F, Vine D, Couto R, Yepez B, Wong E, Moquin A .PGX technology: novel tailor-made and tuneable delivery systems for poorly water-soluble bioactives. Symposium on Pharmaceutical Engineering, Germany, September, 2019.aC
  • Weaver O, Ghosh M, Maximova K, Proctor S, Vine D. Cardiometabolic Risk Factor Assessment using Routine Lab Requisitions following Intervention with Fish and Metformin in women with PCOS. Alberta Diabetes Institute Research Day, Edmonton, Canada, 2019.
  • Weaver O, Ghosh M, Maximova K, Proctor D, Vine DF. Targeting Dyslipidemia and Insulin Resistance using Fish Oil and Metformin in High-Risk Women with Polycystic Ovary Syndrome. Canadian Lipoprotein Conference, Banff, Canada, October 2019.
  • Vine D, Ghosh M, Maximova K, Proctor D. Metformin-Fish Oil Adjunct Therapy Improves Atherogenic Dyslipidemia: ApoB-Remnant Lipoprotein and Triglyceride Levels in Women With Polycystic Ovary Syndrome. Canadian Diabetes and Canadian Society Endocrinology and Metabolism, Winnipeg, Canada, October 2019.
  • Weaver O, Ghosh M, Maximova K, Proctor D, Vine DF. Targeting Dyslipidemia and Insulin Resistance using Fish Oil and Metformin in High-Risk Women with Polycystic Ovary Syndrome. Women and Children’s Health Research Institute Research Day, Edmonton, Canada, November 2019.
  • Weaver O, Proctor E, Proctor S, Ghosh M, Maximova K, Vine DF. Metformin-Fish Oil Adjunct Therapy Improves apoB-Remnant Lipoprotein and Triglyceride Levels in Women with Polycystic Ovary Syndrome. ENDOCRINE SOCIETY, San Francisco, US, March 2020.J Endocr Soc. 2020 May 8;4(suppl 1) SUN-022.https://doi.org/10.1210/jendso/bvaa046.1938
  • Vine DF, Lehner R, Watts R, Horkey M, Ghosh M. Androgens Modulate Lipid Metabolism and Absorption in Control and Polycystic Ovary-Metabolic Syndrome Conditions. ENDOCRINE SOCIETY, San Francisco, US, March 2020. J Endocr Soc. 2020 May 8; 4(Suppl 1): SUN-019.https://doi.org/10.1210/jendso/bvaa046.1389
  • Wilke M, Tran T, Sobool C, Ghosh M and Vine DF. Diet quantity and quality assessment in Canadian women with Polycystic Ovary Syndrome. Canadian Nutrition Society, Edmonton, Canada, May 2020. Applied Physiology, Nutrition, and Metabolism, 2020, 45(4 (Suppl. 1): S1- S56, https://doi.org/10.1139/apnm-2020-0129.
  • Weaver O, Ghosh M, Maximova K, Proctor D, Vine DF. Fish Oil and Metformin Targets Atherogenic Dyslipidemia in Polycystic Ovary Syndrome. Canadian Nutrition Society, Edmonton, Canada, May 2020. Applied Physiology, Nutrition, and Metabolism, 2020, 45(4 (Suppl. 1): S1-S56, https://doi.org/10.1139/apnm-2020-0129.
  • Ton T and Vine DF. Androgen effects on intestinal absorption in a rodent model of PCOS. Canadian Nutrition Society, Edmonton, Canada, May 2020. Applied Physiology, Nutrition, and Metabolism, 2020, 45(4 (Suppl. 1)): S1-S56, https://doi.org/10.1139/ apnm-2020-0129. Uren M and Vine DF. Diet and impact on androgen metabolism. Canadian Nutrition Society, Edmonton, Canada, May 2020. Uren M, Vine D. Diet and impact on androgen metabolism Applied Physiology, Nutrition, and Metabolism, 2020, 45(4 (Suppl. 1)): S51, https://doi.org/10.1139/apnm-2020-0129.
  • Weaver O, Ghosh M, Proctor E, Maximova K, Proctor S, Vine D. Treating Dyslipidemia and Insulin Resistance with Combination Therapy: Fish Oil and Metformin, in High-Risk Women with Polycystic Ovary Syndrome. European Society Endocrinology, Venice, May 2020. https://www.eseondemand.org/#!eposters/resourcetype_ids=3,4&event_ids=282&page=1&tag_ids=2576
  • Donna Faye Vine, Paolo Raggi, Spencer Proctor, Harald Becher.  Androgen and Estrogen Receptor Activation Impacts Cardiac Function in a PCOS-Prone Rodent Model. ENDO Meeting April 2021. J. Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021, Pages A282-A283,  https://doi.org/10.1210/jendso/bvab048.574
  • Vine DF, Proctor S, Ghosh M Raggi P, Becher H. Testosterone Mediates Cardiac Dysfunction and Impairs Fatty Acid Metabolism in Rodent Model Of Polycystic Ovary Syndrome. Canadian Cardiovascular Congress. October 2021, Canadian J Cardiology, in press 2021.

Dr. Rene Jacobs

  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs RL, Vine D (2015) Testosterone modulation of lipid metabolism in pre-diabetes and polycystic ovary syndrome. Mazankowski Alberta Hearth Institute Research Day, Edmonton, AB
  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs RL, Vine D (2015) Testosterone modulation of lipid metabolism in pre-diabetes and polycystic ovary syndrome. Mazankowski Alberta Hearth Institute Research Day, Edmonton, AB
  • Ananthakrishnan G, Proctor S, Ghosh M, Jacobs RL, Vine D (2015) Androgens Differentially Modulate Triglyceride And Cholesterol Metabolism In A Rodent Model Of Pre-Diabetes And Polycystic Ovary Syndrome. Alberta Diabetes Institute, Edmonton, AB, CA
  • Zia Y, Al Rajabi A, Leonard KA, Field C, Mi S, Yuan-Yuan, Zhao Y-Y, Curtis J, Jacobs RL. (2015) Ldlr-/- Mice Lacking Pemt Have Elevated Tmao Levels But Are Protected From High Fat Diet-Induced Atherosclerosis. Mazankowski Alberta Hearth Institute Research Day, Edmonton, AB
  • Zia Y, Rajabi AA, Leonard KA, Mi S, Zhao Y-Y, Field C, Curtis J, Jacobs RL. (2015) Choline supplementation promotes atherosclerosis in Ldlr-/- mice but is independent of plasma trimethylamine-N oxide. Canadian Nutrition Society Annual Meeting, Winnipeg, MB
  • Zia Y, Rajabi A, da Silva RP, Leonard K, Mi S, Zhao Y, Field CJ, Curtis J, Jacobs RL. (2015) Increase in circulating plasma choline increases atherosclerosis independent of plasmaTMAO in LDLR-/- mice. Alberta Diabetes Institute, Edmonton, AB, CA
  • DeRatt B, da Silva RP, Ralat M, Jacobs RL, Gregory JF. (2015) Cystathionine gamma-lyase inhibition in primary human hepatocytes affects the production of hydrogen sulfide biomarkers through the transsulfuration pathway. Experimental Biology Conference, Boston, MA, USA
  • da Silva RP, Leonard K, Kelly K, Nelson R, Jacobs RL (2015) Dietary creatine supplementation prevents fatty liver and impaired lipoprotein secretion in Sprague-Dawley rats fed high-fat diets. Keystones Symposium: Liver Metabolism and Non-Alcoholic Fatty Liver Disease, Whistler, BC, CA
  • Kennelly J*, Ju T, da Silva R, Gao Y, Kelly K, Nelson R, van der Veen J, Willing B, and Jacobs RL (2015) Phosphatidylcholine Metabolism Plays an Important Role in Intestinal Health and Function. Canadian Lipoprotein Conference, Toronto
  • Ju T, Kennelly JP, Gao Y, Kelly K, Willing BP, Jacobs RL (2015) Insufficient Dietary Choline Aggravates Disease Severity in a Mouse Model of Ulcerative Colitis. Alberta Diabetes Institute Research Day, University of Alberta
  • Kennelly JP, Wan S, da Silva R, Kelly K, Jacobs RL (2015) Dietary Creatine Supplementation Reduces Plasma Triglyceride Levels in High Fat Diet-Fed Mice. Alberta Diabetes Institute Research Day, University of Alberta,
  • Gao X, van der Veen J, Vance D, Jacobs RL. (2015) Lack of PEMT alters phospholipid composition causing stress in the hepatic endoplasmic reticulum. DEUEL conference on lipids. Monterey, California, United States
  • Lewis ED, Curtis JM, Jacobs RL, Field CJ. (2015) Choline: the forgotten essential nutrient. Alberta Institute of Agrology Annual Conference, Banff, AB
  • Lewis ED, Richard C, Goruk S, Zhao Y-Y, Jacobs RL, Curtis JM, Field CJ. (2015) Choline concentrations and composition in breast milk is reflective of dietary patterns. Canadian Nutrition Society Annual Meeting, Winnipeg, MB
  • Lewis ED, Richard C, Goruk S, Zhao Y-Y, Jacobs RL, Curtis JM, Field CJ. (2015) Choline concentration and composition in breast milk is determined by maternal diet. WCRHI Research day, Edmonton, AB
  • da Silva R, Ab Aziz N, Nelson R, Kelly KB, Jacobs RL. (2014). Betaine:Homocysteine N-methyltransferase is associated with the lipid droplets and impacts lipid metabolism in McArdle-RH7777 rat hepatoma cells. Canadian Lipoprotein Conference, Saskatoon, 2014-10-02
  • Kupreeva M, Diane A, Jacobs RL, Proctor SD, Vine DF. (2014). Androgen and insulin mediated effects on lipid metabolism in rodent model of polycystic ovary syndrome. Canadian Lipoprotein Conference, Saskatoon,
  • Silva RP, Leonard KA, Kelly KB, Jacobs RL. (2014). Dietary creatine alters lipoprotein secretion in Sprague-Dawley rats with fatty livers induced by a high-fat diet. Canadian Lipoprotein Conference, Saskatoon, 2014-10-02
  • van der Veen JN, Bakala N-Goma JC, Nelson R, Lingrell S, Vance DE, Jacobs RL. (2014). Restoring hepatic PEMT expression by AAV-mediated delivery normalizes the metabolic phenotype of PEMT deficient mice. Canadian Lipoprotein Conference, Saskatoon, 2014-10-02
  • Gao X, van der Veen JN, Fernandez-Patron C, Wagg CS, Fillmore N, Lopaschuk G, Vance DE, Jacobs RL. (2014). Exploring why PEMT-deficient mice are hypothermic upon a cold challenge. Alberta Diabetes Institute Research Day, Edmonton, 2014-09-30
  • Lewis ED, Goruk S, Dellschaft N, Curtis JM, Jacobs RL, Field CJ. (2014). Offspring immune system development is dependent on the amount and form of choline in the maternal diet. Alberta Diabetes Institute Research Day, Edmonton, 2014-09-30
  • van der Veen JN, Bakala N-Goma JC, Nelson R, Lingrell S, Vance DE, Jacobs RL. (2014). The metabolic phenotype of PEMT knockout mice is normalized after AAV-dependent expression of Human PEMT specifically in liver. Alberta Diabetes Institute Research Day, Edmonton, 2014-09-30
  • Lewis ED, Goruk S, Dellschaft N, Curtis JM, Jacobs RL, Field CJ. (2014). Immune development is dependent on the amount and form of choline in the maternal diet. Canadian Nutrition Society Annual Meeting, St. John’s, 2014-06-06
  • Al Rajabi A, Leonard K-A, Vine D., Proctor S, Jacobs RL. Choline status modulates the development of atherosclerosis in LDL receptor knockout mice. Experimental Biology, San Diego, 2014-04-23
  • Da Silva R, Kelly K, Jacobs RL. Hepatic carbohydrate and lipid metabolism are altered in rats fed creatine- supplemented diets. Experimental Biology, San Diego, 2014-04-23
  • Castro GSF, Rajabi A, da Silva R, Nelson R, Kelly SE, Curtis J, Vine DF, Proctor SD and   Jacobs RL. Phosphatidylethanolamine N-Methyltransferase deficiency Increases Dietary Choline Requirement in the LDL Receptor Knockout Mice. 9th International Conference on  Homocysteine and One Carbon Metabolism, Dublin, Ireland, September 8-12, 2013
  • da Silva D, Nelson R, Jacobs RL. Creatine supplementation reduces triacylglycerol accumulation in McArdle 7777 hepatoma cells by stimulating fatty acid oxidation. Experimental Biology, Boston, April 2013
  • Lewis ED, Goruk S, Curtis JM, Jacobs RL, Field CJ. Supplementation with phosphatidylcholine during suckling improves the immune response of the offspring. Experimental Biology, Boston, April 2013
  • Lewis ED, Faily V, Anderson C, NUTR 400 students, Bell RC, McCargar LJ, Curtis JM, Jacobs RL, Field CJ, and the Apron team. Use of a comprehensive choline database to estimate choline intake of Albertan women. AIHN Graduate Student Poster Competition, Edmonton, AB. February 2013 [Awarded 1st place]
  • Faily V, Lewis ED, Tumbare R, Curtis JM, Jacobs RL, Field CJ, and the APrON team Development and use of a food frequency questionnaire choline database to estimate choline intake prior to pregnancy in the APrON cohort. WCHRI Research Day. Edmonton, AB, 2012
  • Lewis ED, Curtis JM, Jacobs RL, Field CJ Maternal phosphatidylcholine intake during suckling improves immune response of the offspring. WCHRI Research Day, Edmonton, AB, 2012 (Oral Presentation)
  • Lewis ED, Curtis JM, Jacobs RL, Field CJ The impact of the form of choline in the maternal diet on the development of the immune system in the offspring. AFNS 601 Departmental Seminar, University of Alberta, Edmonton AB, 2012 (Oral Presentation)
  • Walker AK, Niebergall L, Jacobs RL, Watts J, Vance D, Naar A. Alternative Mechanisms of Sterol-Regulatory Element-binding Protein 1 (SREBP1) Activation. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Gao X, van der Deen J, Lingrell S, Vance D, Jacobs RL. Vagus Nerve signals contribute to the resistance of phosphatidylethanolamine N-methyltransferase deficient mice to high fat diet induced obesity. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Da Silva RP and Jacobs RL. Creatine Supplementation alters hepatic lipid metabolism in vitro and in vivo. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Kelly KB, ab Aziz N, Goruk S, Curtis JM, Vine DF, Proctor SD, Field CJ, Jacobs RL. Intestinal lipid metabolism in the lactating, choline-deficient rat. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Sheedfar F, Sung MM, Miquilena-Colina ME, Chavez E, Jacobs RL, Febbraio M, Hofker MH, Garcia-Monzon C, Dyck JR, Koonen DP. Lipid-mediated Inflammation and Susceptibility toward Nonalcoholic fatty liver disease with age. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Wang F, Diane A, Kelly SE, Jacobs RL, Proctor SD, Vine DF. Metformin and Flutamide Attenuate plasma and lymphatic ApoB48 and ApoB100 Concentrations in the JCR:LA-cp Rat: A model of Insulin Resistance and Polycystic Ovary Syndrome. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Jacome-Sosa, Wang Y, Borthwick F, Jacobs RL, Uwiera R, Nelson R, Reaney MM, Shen J, Quiroga A, Lehner R, Proctor SD. Supplmentation of dairy fat with T-11 vaccenic acid improves body fat composition and reduces both intestinal and hepatic lipid storage and secretion in a model of metabolic syndrome (JCR:LA-cp Rat). Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Niebergall, LJ, Jacobs RL, Vance DE, Naar AM, Walker AK. Ablation of phosphatidylcholine biosynthesis activates sterol-regulatory element-binding protein 1 independently of endoplasmic reticulum stress. Frontiers in Lipid Biology, Banff, September 5-8, 2012
  • Lewis ED, Dellschaft N, Goruk S, Curtis JM, Jacobs RL, Field CJ Maternal choline intake during suckling alters immune development in the offspring. Canadian Nutrition Society Annual Meeting, Vancouver, BC. May, 2012.
  • Lewis ED, Poskus CM, Curtis JM, Jacobs RL, Field CJ, Creation of a Comprehensive Choline Database: The Development and Application in Calculating Choline Consumption of Pregnant Albertan Women. Alberta Institute of Human Nutrition Graduate Poster Competition, Edmonton, March, 2012
  • Rodriguez Dimitrescu A., Jacobs RL, Proctor S, Vine D. Polycystic ovary syndrome: Exploring mechanisms of atherogenic dyslipidemia in a rodent model. Canadian Diabetes Association Meeting. October 2011.
  • Kelly K, Xiong Y, Allen RH, Stabler SP, Field CJ, Curtis JM, Jacobs RL. Under- or Over-Supply of Dietary Folic Acid Impairs Hepatic Phosphatidylcholine Production. Canadian Lipoprotein Conference. Halifax, NS. 2011
  • Ab Aziz N, Kelly KB, Légaré M, Leonard K-A, Dellschaft N, Goruk S, Curtis J, Vine D, Proctor, S, Field CJ, Jacobs RL. Choline deficiency impairs intestinal lipid metabolism in the lactating rat. Canadian Oil Chemists Society Meeting, Edmonton, AB. 2011
  • Ewaschuk JB, Jacobs R, Nelson R, Newell M, Field CJ DOCOSAHEXAENOIC ACID ALTERS CELL DEATH, CANCER AND CELL-CYCLE SIGNALING NETWORKS IN BREAST CANCER CELL LINES. Canadian Oil Chemists Society Meeting, Edmonton, AB. 2011
  • Yeping Xiong Y, Zhao Y-Y, Goruk S, Oilund K, Field C, Jacobs R, Curtis J. Validation of a LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues. Canadian Oil Chemists Society Meeting, Edmonton, AB. 2011
  • Rodriguez Dimitrescu A., Jacobs RL, Proctor S, Vine D. POLYCYSTIC OVARY SYNDROME: EFFECTS OF FLUATMIDE AND METFORMIN ON ATHEROGENIC DYSLIPIDEMIA IN A RODENT MODEL. ADI Research Day, Edmonton, Sept 2011
  • Kelly K, Xiong Y, Curtis JM, Allen RH, Stabler SP, Field CJ, Jacobs RL. Hepatic PC levels are reduced in rats fed either a folate-deficient or a folate-excess diet. International Conference on Homocysteine Metabolism. Lisbon, Portugal, June 2011.
  • Rodriguez Dimitrescu A., Jacobs RL, Proctor S, Vine D. Understanding mechanisms of atherogenic dyslipidemia in a rodent model of polycystic ovary syndrome. Alberta Institute of Human Nutrition Research Day, Edmonton, March 2011.
  • Kelly K, Simon Lamarre S, Nelson R, King-Jones K, Field C, Proctor S, Brosnan M, Brosnan J, Jacobs RL. Folic Acid Fortification: Are We Getting Too Much of a Good Thing? AIHN Symposium. “The Scientification of Eating: From Research to Reality.” University of Alberta. Mar 15, 2011.
  • Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall L, Vance DE, Hart AC, Naar AM. Control of One-carbon cycle genes by SREBP-1 links S-adenosylmethionine production, phosphatidylcholine biosynthesis and Hepatic lipogenesis. Deuel Conference on Lipids, Sonoma, March 2011.
  • Niebergall LJ, Jacobs RL, Chaba T and Vance DE. Hepatic deletion of CTP:phosphocholine cytidylyltransferase-α reduces hepatic phosphatidylcholine which leads to the development of non-alcoholic steatohepatitis. Deuel Conference on Lipids, Sonoma, March 2011.
  • Ling J, Jacobs RL, Zhu LF, Chaba T, Vance DE. Survival of Pemt-/- mice after 70% partial hepatectomy is improved with increased hepatic PC:PE ratio and an associative decrease in inflammation. Deuel Conference on Lipids, Sonoma, March 2011
  • Rodriguez Dimitrescu A., Proctor S, Jacobs RL, Vine D. Lipid metabolism in a rodent model of polycystic ovary syndrome: effects of metformin and flutamide. Women and Child Research Institute Annual Research Day at the Westin Hotel in Edmonton , Nov 26, 2010
  • Iglinski P, Goruk S, Dixon A, Jacobs RL, Curtis J, Field CJ. Dietary Choline Influences the Distribution of Immune Cells in the Spleens of Dams during Lactation. Women and Child Research Institute Annual Research Day at the Westin Hotel in Edmonton , Nov 26, 2010
  • Kelly K, Lamarre S, Nelson R, King-Jones K, Brosnan ME, Brosnan JT, and Jacobs RL. B-vitamin status alters lipid metabolism in rats. Women and Child Research Institute Annual Research Day at the Westin Hotel in Edmonton, Nov 26, 2010
  • Rodriguez Dimitrescu A., Proctor S, Jacobs RL, Vine D. Lipid Metabolism in the JCR:LA rodent model of Polycystic Ovary Syndrome: effects of Flutamide and Metformin. Canadian Lipoprotein conference. Niagara Falls, Ontario, Oct 21-24, 2010.
  • Rodriguez Dimitrescu A., Proctor S, Jacobs RL, Vine D. EFFECTS OF FLUTAMIDE AND METFORMIN ON LIPID METABOLISM IN A RODENT MODEL OF POLYCYSTIC OVARY SYNDROME. Alberta Diabetes Institute Research Day, Edmonton, October 5th, 2010
  • Iglinski P, Goruk S, Dixon A, Samuelson S, Jacobs RL, Field CJ. Dietary Choline Influences the Distribution of Immune Cells in the Spleens of Dams During Lactation. AFNS summer student symposium on Aug 19, 2010
  • Oilund K, Field CJ, Jacobs RL, and Curtis J. Screening Dietary Recalls to Determine the Top Contributors of Choline & Betaine in the Diet of Pregnant Albertan Women, NSERC undergraduate research day, University of Alberta, Edmonton, August 2010
  • Kelly K, Lamarre S, Nelson R, King-Jones K, Brosnan ME, Brosnan JT, and Jacobs RL. Do folate- and vitamin B12-deficiency affect phosphatidylcholine metabolism in rats? FASEB summer Research Conference, Carefree, Arizona, August 2010
  • Jacobs RL, Zhao Y, Koonen DPY, Lingrell S, Dyck JRB, and Vance DE. Choline: a novel regulator of whole-body energy metabolism. FASEB summer Research Conference, Carefree, Arizona, August 2010
  • Paramadayalan SS, Erickson B, Ko KWS, Kelly K, Yao Z, King-Jones K, Jacobs RL, and Lehner R. Decreased triacylglycerol storage and secretion in hepatocytes expressing endoplasmic reticulum-associated hepatic lipase. FASEB summer Research Conference, Steamboat Grand Resort, Steamboat Springs, Colorado, July 25-July 30, 2010
  • Niebergall L, Jacobs RL, Chaba T and Vance DE. CDP-choline attenuates non-alcoholic steatohepatitis in hepatic CTP: phosphocholine cytidylyltransferase alpha deficient mice. Gordon Conference on the Molecular and Cell biology of Lipids, July, 2010
  • Kelly K, Lamarre S, Nelson R, King-Jones K, Brosnan ME, Brosnan JT, and Jacobs RL. Is phosphatidylcholine metabolism altered in folate- and vitamin B12-deficient rats? Canadian Nutrition Society Conference, Edmonton, 2010
  • Pant A, Xue H, Kelly K, King-Jones K, Jacobs RL, Baracos VE and Mazurak VC. Hepatic gene alterations induced by irinotecan are partly reversed by a diet containing fish oil. Canadian Nutrition Society Conference, Edmonton, 2010
  • Kelly K, Lamarre S, Nelson R, King-Jones K, Brosnan JT, Jacobs RL. Effects of Folate and Vitamin B12 on Phospholipid Metabolism in Rats. Canadian Lipoprotein Conference, Windsor, ON, October 2009.
  • Niebergall LJ, Jacobs RL, Chaba T, and Vance DE. Hepatic CTP: phosphocholine cytidylyltransferase alpha deficient mice are susceptible to diet induced non-alcoholic steatohepatitis. Gordon Conference on the Molecular and Cell Biology of Lipids, July 2009.
  • Jacobs RL, Zhao Y, Koonen DPY, Sletten T, Lingrell S, Cao G, Peake DA, Kuo MS, Kennedy BP, Dyck JRB, and Vance DE. A role for choline in diet-induced obesity. The 1st National Obesity Summit, Kananaskis, AB, May 2009.
  • Jacobs RL, Zhao Y, Koonen DPY, Sletten T, Lingrell S, Zhu LF, Dyck JRB, Vance DE. Vagal signaling is essential in preventing obesity and insulin resistance in mice with impaired hepatic phosphatidylcholine biosynthesis. Canadian Lipoprotein Conference, Whistler, BC, October 2008.
  • Niebergall LJ, Jacobs RL, Vance DE. The role of phosphatidylcholine in the pathogenesis of steatohepatitis. Canadian Lipoprotein Conference, Whistler, BC, October 2008.
  • Cole LK, Jacobs RL, Vance DE. Causes of tamoxifen-induced steatosis in mouse liver. Canadian Lipoprotein Conference, Whistler, BC, October 2008.
  • Jacobs RL, Zhao Y, Koonen DPY, Methot N, Zhu LF, Kennedy B, Dyck JRB, Vance DE. Vagal signaling is essential in preventing obesity in mice with impaired hepatic phosphatidylcholine biosynthesis. Mazankowski Heart Congress, Edmonton, June 2008.
  • Sung MM, Koonen DPY, Jacobs RL, Soltys CL, Febbraio M, Vance DE, Dyck JRB. Increased fatty acid transorter expression induced by high fat diet in aged mice contributes to obesity-related cardiomyopathies. Mazankowski Heart Congress, Edmonton, June 2008.
  • Lingrell S, Jacobs RL, Vance DE. Adenovirus mediated alteration of phosphatidylethanolamine N-methyltransferase expression in vivo. Experimental Biology 08, San Francisco, April 2008
  • Jacobs RL, Zhao Y, Koonen DPY, Methot N, Kennedy B, Dyck JRB, Vance DE. Phosphatidylethanolamine N-methyltransferase Deficiency Protects Mice Against Diet-induced Obesity and Insulin Resistance. Deuel Conference on Lipids, Loews Coronado Bay Resort, California, March 2008
  • Jacobs RL, Zhao Y, Methot N, Dyck JRB, Kennedy B, Vance DE. Phosphatidylethanolamine N-methyltransferase Deficiency Enhances Insulin Sensitivity and Protects Mice Against Diet-induced Obesity. Canadian Lipoprotein Conference, Quebec, October 2007
  • Koonen, DPY, Jacobs RL, Febbraio M, Young ME, Ong H, Vance DE, Dyck JRB CD36 mediates hepatic fatty acid uptake and triglyceride storage and contributes to dyslipidemia associated with diet-induced obesity, June 2007
  • Jacobs RL, Francis GA, and Vance DE. Hepatic PC biosynthesis is a key regulator of plasma HDL: Studies in the liver-specific CTP:phosphocholine cytidylyltransferase- knockout mouse. Deuel Conference on Lipids, Borrego Springs, March 2007
  • Jacobs RL, and Vance DE. Liver-specific phosphocholine cytidylyltransferase-α knockout mice develop insulin resistance despite having lower plasma lipid levels. Experimental Biology, San Francisco, April 2006
  • Lingrell S, Jacobs RL, Dyck JR, Vance DE Inhibition of hepatic phosphatidylcholine synthesis by AICAR and phenformin is independent of AMP-activated protein kinase (AMPK) activation. San Francisco, April 2006
  • Koonen DPY,Jacobs RL, Young MME, Vance DE, Febbraio M, and Dyck JRB. Short-term Overexpression of CD36 in the Liver Augments Hepatic Lipid Storage and VLDL-triglyceride Secretion: Implications for Diet-Induced Obesity and Type 2 Diabetes. Circulation. 2006; 116 (18):II-323.
  • Koonen DPY,Jacobs RL, Young MME, Vance DE, Febbraio M, and Dyck JRB. Hepatic Lipid Storage and Secretion is Mediated by CD36: Implications for Diet-Induced Obesity and Type 2 Diabetes. Cardiac Sciences Day 2006, University of Alberta, Canada.
  • Jacobs RL, Devlin C, Tabas I, Vance DE. CTP:phosphocholine cytidylyltransferase-α deficient hepatocytes does not produce enough phosphatidylcholine for cell division. FASEB 2005. San Diego, April 1-4, 2005
  • Jacobs RL, Robichaud J, Devlin C, Tabas I, Francis G, Vance DE. CTP:phosphocholine Cytidylyltransferase-α deficient hepatocytes have decreased lipid secretion and cholesterol uptake. Canadian Lipoprotein Conference. Banff, Alberta, Oct. 21-24, 2004.
  • Stead LM, Jacobs RL, Devlin C, Tabas I, Brosnan ME, Brosnan JT, Vance DE. Phospholipid methylation regulates homocysteine metabolism. Canadian Lipoprotein Conference. Banff, Alberta, Oct. 21-24, 2004.
  • Jacobs RL, Stead LM, Devlin C, Tabas I, Brosnan ME, Brosnan JT, Vance DE. Phosphatidylethanolamine-methylation is an important regulator of plasma homocysteine in mice. FASEB-biological methylation. Vermont, July 10-15, 2004.
  • Jacobs RL, Devlin C, Tabas I, Vance DE. CTP:phosphocholine cytidylyltransferase-α deficient hepatocytes have decreased VLDL secretion and cholesterol efflux. 5th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology. San Francisco, May 6-8, 2004.
  • Jacobs RL, Stead LM, Devlin C, Noga AA, Yang Z, Tabas I, Brosnan ME, Brosnan JT, Vance DE. Methylation demand and homocysteine metabolism: studies on Pemt-/- and liver-specific CTα knockout mice. J. Inherit. Metab. Dis. (Suppl) 26:57. Fourth International Conference on Homocysteine Metabolism, Basel, Switzerland, June 29-July 3, 2003.
  • Jacobs RL, Devlin C, Tabas I, Vance DE. Liver-specific knockout of CTP:phosphocholine Cytidylyltransferase-α reveals its sex-dependent role in hepatic lipid and lipoprotein metabolism. FASEB 2003, San Diego, April, 2003
  • Jacobs RL, Tabas I, Vance DE. Role of CTP:phosphocholine cytidylyltransferase-alpha in hepatic lipid and lipoprotein metabolism. (2002) Canadian lipoprotein conference. Banff, October 17-20.
  • Ratnam S, Wijekoon E, Jacobs RL, Brosnan ME, Brosnan JT (2002) Regulation of homocysteine metabolism by insulin. Proceedings of the Canadian Diabetes Association. Vancouver, October 2-5.
  • Hasslet M, Hall B, Jacobs R, Brosnan M (2002) Regulation of Proline Catabolism. Proceeding of Canadian Federation of Biological Sciences, June 12-15.
  • Jacobs RL, Ratnam S, Stead LM, Brosnan ME, and Brosnan JT (2001) Cystathionine Beta-Synthase: Regulation by Insulin and Counter-Regulatory Hormones. 3rd International Homocysteine Congress. Sorrento, Italy, July 1-5.
  • Stead L, Au K, Jacobs R, Brosnan M, Brosnan J (2001) Methylatation demand and homocysteine metabolism: Effects of Dietary provision of creatine and guanidinoacetate. 3rd International Homocysteine Congress. Sorrento, Italy, July 1-5.
  • Jacobs RL, Ratnam S, Stead LM, Brosnan ME, and Brosnan JT (2000) In vivo and in vitro regulation of homocysteine metabolism: role of insulin and counter-regulatory hormones. FASEB Conference 2000-Folic acid, vitamin B12 and one carbon metabolism. August 5-10.
  • Jacobs RL, Stead LM, Brosnan ME, and Brosnan JT (2000) Effects of glucagon treatment on homocysteine metabolism in the rat. 18th International Congress of Biochemistry and Molecular Biology. Birminghan, UK. July 16-20.
  • Ratnam S, Jacobs RL, Brosnan ME, Brosnan JT (2000) Regulation of cystathionine beta-synthase expression by insulin. American Society for Biochemistry and Molecular Biology, Boston. FASEB J, 14, Abstract 443.
  • Jacobs RL, Brosnan ME, and Brosnan, JT (2000) Hormonal regulation of homocysteine metabolism. Aldrich interdisciplinary conference. Memorial University of Newfoundland. Feb 21.
  • Jacobs RL, Stead LM, Brosnan ME, and Brosnan JT (1999) Hypothyroid rats exhibit decreased plasma homocysteine unlike human hypothyroidism. FASEB Journal. Vol 13:381.
  • Brosnan JT, House JD, Jacobs RL, Stead LM, Brosnan ME (1998) Homocysteine Metabolism. Thirty-ninth International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues. Indianapolis, Indiana. October 5-6, 1998.
  • Jacobs RL, Stead LM, House JD, Brosnan ME, Brosnan JT (1998) Is homocysteine metabolism hormonally regulated? Studies in the streptozotocin-induced diabetic rat. The Netherlands Journal of Medicine, Vol 52, supplement: S43
  • Jacobs RL, House J, Brosnan M, Brosnan J. (1997) Homocysteine metabolism in the streptozotocin-diabetic rat. Canadian Journal of Diabetes Care, Vol 21. No 3, supplement: 3
  • Jacobs R, House J, Brosnan M, Brosnan J (1997) Homocysteine metabolism in the streptozotocin-induced diabetic rat. International Congress of Nutrition, PT 224
  • Brosnan JT, Jacobs RL, House JD, Brosnan ME. (1997) Homocysteine metabolism in the streptozotocin-diabetic rat. Proceeding of Canadian Federation of Biological Societies,

Dr. Caroline Richard

  • Azarcoya-Barrera J, Patel D, Field J. C. Goruk S, Pouliot Y, Curtis M. J. Jacobs R, Richard C*. A diet high in lipid soluble forms of choline modulates gut-associated immune function in Sprague-Dawley dams. Oral presentation the American Society of Nutrition; Virtual meeting  June 7-10, 2021.  Current Developments in Nutrition, 5 (Supplement 2), 1119.  https://doi.org/10.1093/cdn/nzab061_003.  Impact Factor: 2.91
  • Rayane Braga Tibaes J, Barreto Silva MI, Blanco P, Wollin B, Makarowski A, Vine D, Tsai S, Richard C*. Expression of CD25 in Individuals with Obesity with or without Insulin Resistance After following a North American Diet. Oral presentation the American Society of Nutrition; Virtual meeting June 7-10, 2021. Current Developments in Nutrition5   (Supplement 2), 1122–1122. https://doi.org/10.1093/cdn/nzab061_006. Impact Factor: 2.91
    This abstract was selected as a finalist for the Emerging Leaders in Nutrition Science Abstract  Recognition Award Program which recognizes the very best research presented by students and young investigators during Nutrition 2021 Live Online in the Nutritional Immunology and Inflammation/ Immunometabolism Topical Area.
  • Picard K, Griffiths M, Brunelle L, Mager DR, Richard C*. Sex differences in diet quality and nutrient in adults living with chronic kidney disease. Poster presented at the American Society of Nutrition; Virtual meeting June 7-10, 2021. Current Developments in Nutrition,    5(Supplement 2), pp.859-859.  https://doi.org/10.1093/cdn/nzab047_022. Impact Factor: 2.91
  • Rusnak T, Azarcoya-Barrera J, Wollin B, Thomsen A, Makarowski A, Jacobs R, Richard C*. A high-fat diet containing 50% Egg-phosphatidylcholine increased the proportion of T cells expressing a memory marker in male Wistar rats. Poster presented at the American Society of  Nutrition; Virtual meeting June 7-10, 2021. Current Developments in Nutrition, Volume 5, Issue Supplement 2, June 2021, Page 1140. https://doi.org/10.1093/cdn/nzab061_024. ImpactFactor: 2.91
  • She Y, Wang K, Willing B, Tsai S, Proctor SD, Richard C*. Dairy fat consumptions do not modulate immune functions in a swine model of insulin resistance: a preliminary analysis. Poster presented at the American Society of Nutrition; Virtual meeting June 7-10, 2021.  Current Developments in Nutrition, 5 (Supplement 2), 1141-1141. https://doi.org/10.1093/cdn/nzab061_025. Impact Factor: 2.91
  • Wang K, She Y, Mangat R, Makarowski A, Roy BC, Bruce HB, Dyck MK, Richard C*, Proctor SD*. Exploring increased intestinal lipid absorption and identifying strategies to improve pork quality in low-birth-weight swine. Oral presentation the American Society of Nutrition;   Virtual meeting June 7-10, 2021. Current Developments in Nutrition, Volume 5, Issue Supplement 2, Page 547.  https://doi.org/10.1093/cdn/nzab042_014. Impact Factor: 2.91
  • Barreto Silva MI, Rayane Braga Tibaes J, Klein R.S.T.M, Richard C*. Sex differences in Patients with Non-Dialysis Dependent Chronic Kidney Disease on Serum Cytokines. Poster presented at the American Society of Nutrition; Virtual meeting June 7-10, 2021. Published in https://doi.org/10.1093/cdn/nzab061_004.  Impact Factor: 2.91
  • Patel D, Goruk S, Richard C, Field CJ*. Supplementing docosahexaenoic and arachidonic acid during suckling period is beneficial for developing tolerance to egg protein in allergy prone Brown Norway rats. Poster presented at the American Society of Nutrition; Virtual meeting June 7-10, 2021. Current Developments in Nutrition, Volume 5, Issue Supplement 2, Page 1136. https://doi.org/10.1093/cdn/nzab061_020
  • Picard, K., Griffiths, M., Richard, C. Updates in medical nutrition therapy for adults living with chronic kidney disease. Presented at Canadian Nutrition Society Annual Conference in April 2021 (Webinar). Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23.
  • Wollin B, Rayane Braga Tibaes J, Azarcoya-Barrera J, Veida-Silva H, Makarowski A, Goruk S, Richard C*. Mechanisms behind the T-cell response to a high-fat diet differ between male and female Wistar rats. Poster presented at the Canadian Nutrition Society Conference; Edmonton, AB. May 7-9, 2020. Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • Aldana-Hernández P, Azarcoya-Barrera J, Leonard KA, Goruk S, Richard C, Curtis JM, Field CJ, Jacobs RL*. Dietary phosphatidylcholine supplementation decreased atherosclerosis development in Ldlr-/- mice. Poster presented at the Canadian Nutrition Society Conference; Edmonton, AB. May 7-9, 2020. Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23. She was selected for the oral presentation competition.
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • Patel D, Goruk S, Richard C, Field CJ*. Supplementation of neonatal diet with docosahexaenoic acid and arachidonic acid improves immune function and the development of oral tolerance. Poster presented at the Canadian Nutrition Society Conference; Edmonton, AB.  May 7-9, 2020. Applied Physiology, Nutrition, and Metabolism.  Impact Factor:  2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • She Y, Wang K, Willing B, Tsai S, Proctor S, Richard C*. Effects of consuming dairy product on the cardiometabolic risk profile in a swine model of insulin resistance. Poster presented at the  Canadian Nutrition Society Conference; Edmonton, AB. May 7-9, 2020.  Applied  Physiology,          Nutrition, and Metabolism.  Impact Factor: 2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • Picard K, Barreto Silva MI, Mager DR, Richard C*. Eats donuts not bananas? Graphic Abstract/poster presented at the Canadian Nutrition Society Conference; Edmonton, AB. May 7-9, 2020.  Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • Picard K, Senior P, Jindal K, McKenzie J. Richard C*, Mager DR*. A longitudinal examination of Mediterranean diet scores and impact on health outcomes in patients with diabetic nephropathy. Poster presented at the Canadian Nutrition Society Conference; Edmonton, AB.  May 7-9, 2020. Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstract submitted have not been presented in a live session (some were presented remotely).
  • Azarcoya-Barrera J, Wollin B, Veida-Silva H, Makarowski A, Goruk S, Jacobs R, Richard C*. Phosphatidylcholine attenuates T cell dysfunction in high-fat diet fed male Wistar rats. Published abstract presentation at the Canadian Nutrition Society Conference; Edmonton, AB.  May 7-9, 2020. Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23
    The 2020 CNS conference was cancelled due to COVID-19 and although some of the abstractsubmitted have not been presented in a live session (some were presented remotely).
  • Field J.C, Lewis ED, Goruk S, Richard C, Jacobs RL, Curtis JM. The amount and form of choline in the maternal diet alters choline content of breast milk and immune development in the infant. Oral presentation at the FASEB summer conference: The Origins and Benefits of Biologically Active Components in Human Milk Conference.  July 21-26, 2019, West Palm Beach Florida. (30 min invited talk).  FASEB Journal. Impact Factor: 5.19
  • Azarcoya-Barrera J, Field J.F, Goruk S, Pouliot Y, Curtis M.J, Jacobs L.R, Richard C*. Feeding a mixture of choline forms derived from buttermilk to lactating dams modulates breast milk composition and improves the maturation of the immune system in offspring. Poster presentation at the Canadian Nutrition Society. May 2-4, 2019, Sheraton on the Falls, Niagara Fall (Ontario). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Patel D, Goruk S, Newell M, Richard C, Chen G, and Field J.C*. Feeding a bioactive oil enriched in stearidonic acid during suckling and weaning improves immune development in neonatal rats. Poster presentation at the Canadian Nutrition Society. May 2-4, 2019, Sheraton on the Falls, Niagara Fall (Ontario). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Richard C, Lewis D. E, Goruk S, Jacobs L. R, Curtis M. J, Field J. C*. Feeding a maternal diet containing a mixture of choline forms during lactation modulates choline breast milk composition and improves T cell function in suckled offspring. Poster presentation at the Canadian Nutrition Society. May 25-27, 2017, Hotel Bonaventure, Montréal (Québec). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Lewis D. E, Richard C, Goruk S, Jacobs L. R, Curtis M. J, Field J. C*. Feeding a mixture of choline forms representative of human intake during lactation improves offspring growth and maternal immune function. Poster presentation at the Canadian Nutrition Society. May 25-27, 2017, Hotel Bonaventure, Montréal (Québec).  Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23
  • Richard C, Lewis D. E, Goruk S, Field J. C*. Feeding a high docosahexaenoic acid maternal diet during lactation beneficially impact the offspring’s immune function and establishment of oral tolerance. Oral and Poster presentation at the Canadian Nutrition Society. May 5-7, 2016, Hilton Lac-Leamy Gatineau-Ottawa Hotel, Gatineau-Ottawa (ON). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Lewis D. E, Richard C, Goruk S, Dellschaft S. N, Jacobs L. R, Curtis M. J, Field J. C*. Regardless of concentration, providing choline in the diet during lactation as phosphatidylcholine compared to free choline improves immune development in the offspring. Poster presentation at the Canadian Nutrition Society. May 5-7, 2016, Hilton Lac-Leamy Gatineau-Ottawa Hotel, Gatineau-Ottawa (ON).  Applied Physiology, Nutrition, and Metabolism.  Impact Factor: 2.23
  • Richard C, Lewis D. E, Goruk S, Field J. C*. Feeding a Maternal Diet Enriched in Docosahexaenoic Acid to Lactating Dams Improves the Ex Vivo Tolerance Response to Egg Protein in Suckled Pups. Oral presentation at the Experimental Biology (EB). April 2-6 2016, San Diego Convention Center, San Diego (CA); In addition to a poster presented at the ASN’s Emerging Leaders in Nutrition Science Poster Competition. FASEB Journal. Impact Factor: 5.19
  • Lewis D. E, Richard C, Goruk S, Dellschaft S. N, Curtis M. J, Jacobs L. R, Field J. C*. Offspring immune system development is dependent on the amount and form of choline in the maternal diet during suckling. Oral presentation at the Experimental Biology (EB). April 2-6, 2016, San Diego Convention Center, San Diego (CA). FASEB Journal. Impact Factor: 5.19
  • Richard C, Goruk S, Field J. C*. Feeding a docosahexaenoic acid rich diet during the suckling and weaning period modulates immune function in offspring. Poster presentation at the Federation of American Societies for Experimental Biology Science Research Conference (FASEB SRC) on Nutritional Immunology: Role in Health and Disease. July 26-31, 2015, Lisbon Marriott Hotel, Lisbon, Portugal. FASEB Journal. Impact Factor: 5.19
  • Richard C, Lewis D. E, Goruk S, Field J. C*. Feeding a diet enriched in docosahexaenoic acid to lactating dams improves the ex vivo response to egg protein in suckled pups. Poster presented at the Canadian Nutrition Society. May 28-30, 2015, Winnipeg Convention Center, Winnipeg (MB). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Lewis D. E, Richard C, Goruk S, Zhao Y.Y, Jacobs L. R, Curtis M. J, Field J. C*. Choline concentrations and composition in breast milk is reflective of dietary patterns. Oral presentation at the Canadian Nutrition Society. May 28-30, 2015, Winnipeg Convention Center, Winnipeg (MB). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Wattar N, Richard C, Goruk S, Field J. C*, and the APrON study team. Establishing the relationship between maternal status and breast milk composition of docosahexaenoic and arachidonic fatty acids. Poster presented at the Canadian Nutrition Society. May 28-30, 2015, Winnipeg Convention Center, Winnipeg (MB).  Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Richard C, Goruk S, Field J. C*. Feeding a docosahexaenoic acid rich diet during the suckling and weaning period modulates immune function in offspring. Oral presentation at the Experimental Biology (EB). March 28-April 1, 2015, Boston Convention and Exhibition Center, Boston (MA); In addition to a poster presented at the ASN’s Emerging Leaders in Nutrition Science Poster Competition. FASEB Journal. Impact Factor: 5.19
  • Leclerc M, Ooi E. M, Couture P, Richard C, Desroches S, Marin J, Tremblay A, Lamarche B*. Inter-relationship Between the In vivo Metabolism of Apolipoprotein B100 Containing Lipoproteins and LDL Particle Size Phenotype and LDL Particle Number. Oral presentation at the Experimental Biology (EB). March 28-April 1, 2015, Boston Convention and Exhibition Center, Boston (MA). FASEB Journal. Impact Factor: 5.19
  • Richard C, Couture P, Desroches S, Lamarche B*. Impact of the Mediterranean diet and weight loss on plasma apolipoprotein CIII concentrations in men with metabolic syndrome. Poster presented at the Canadian Nutrition Society. May 30-June 2 2013, Loews Hôtel Le Concorde, Québec City (Qc). Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Richard C, Couture P, Desroches S, Lamarche B*. Diète Méditerranéenne, perte de poids et métabolisme de l’apolipoprotéine B. Affiche présentée à la 14e réunion annuelle de la Société          québécoise de lipidologie, de nutrition et de métabolisme. Mai 9-10, 2013, Château Bonne          Entente, Québec (Qc).  
  • Richard C, Couture P, Desroches S, Lamarche B*. The Mediterranean diet with and without weight loss improves several features of low-density lipoprotein metabolism in men with metabolic syndrome. Poster presented at the Arteriosclerosis, Thrombosis, Vascular Biology. May 1-3, 2013, The Dolphin Hotel, Lake Buena Vista, Fla, USA. Arteriosclerosis, Thrombosis, Vascular Biology, 2014 Feb;34(2):433-438.  PMID: 24265415.  Impact Factor: 8.3
  • Richard C, Couture P, Esther Ooi, Desroches S, Lamarche B*. Effect of the Mediterranean diet on apolipoprotein B kinetic in men with metabolic syndrome. Oral presentation at the Arteriosclerosis, Thrombosis, Vascular Biology (Kinmet). April 30, 2013, The Dolphin Hotel, Lake Buena Vista, Fla, USA. Arteriosclerosis, Thrombosis, Vascular Biology.  Impact Factor: 8.3
  • Richard C, Couture P, Desroches S, Lamarche B*. Effet de la diète Méditerranéenne sur la cinétique de l’apolipoprotéine AI chez des hommes avec syndrome métabolique. Affiche présentée à la 13e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Mai 10-11, 2012, Château Bonne Entente, Québec (Qc).
  • Baril-Gravel L, Richard C, Couture P, Jenkins DA, West S, Kris-Etherton P, Jones P, Lamarche B*. Impact de différentes huiles sur les concentrations plasmatiques d’adiponectine : Une étude clinique contrôlée randomisée en chassé-croisé à double-insu. Affiche présentée à la 13e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Mai 10-11, 2012, Château Bonne Entente, Québec (Qc).
  • Cyr A, Abdullah M, Richard C, Jones P, Couture P, Lamarche B*. Impact de la consommation de produits laitiers sur la tension artérielle chez des sujets en santé mais avec un profil inflammatoire légèrement détérioré. Affiche présentée à la 13e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Mai 10-11, 2012, Château Bonne Entente, Québec (Qc).
  • Richard C, Couture P, Desroches S, Benjannet S, Seidah NG, Lamarche B*. Effet de la diète Méditerranéenne et de la perte de poids sur le métabolisme du cholestérol chez des hommes avec un syndrome métabolique. Affiche présentée à la 11e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Avril 29-Mai 1, 2010, Château Bonne Entente, Québec (Qc).
  • Richard C, Couture P, Desroches S, Lamarche B*. Effect of weight loss on apolipoprotein AI kinetic in men with metabolic syndrome. Oral presentation at the Arteriosclerosis, Thrombosis, Vascular Biology (Kinmet). April 17, 2012, Hilton Chicago, Chicago, IL, USA. Arteriosclerosis, Thrombosis, Vascular Biology, 2013 Jan;54(1)232-7. PMID: 24499022.  Impact Factor: 8.3
  • Richard C, Couture P, Desroches S, Lamarche B*. Impact of the Mediterranean diet on apolipoprotein A-I kinetic in men with metabolic syndrome. Poster presented at the Arteriosclerosis, Thrombosis, Vascular Biology. April 18-20, 2012, Hilton Chicago, Chicago, IL, USA. Arteriosclerosis, Thrombosis, Vascular Biology.  Impact Factor: 8.3
  • Richard C, Couture P, Desroches S, Lamarche B*. Impact of the Mediterranean diet and weight loss on adipokines in men with metabolic syndrome. Poster presented at the Canadian Nutrition Society. June 2-4, 2011, University of Guelph, Guelph, Ontario (ON).  Applied Physiology, Nutrition, and Metabolism. Impact Factor: 2.23
  • Richard C, Couture P, Desroches S, Lamarche B*. Effet de la diète Méditerranéenne et de la perte de poids sur la taille des particules LDL chez des hommes avec syndrome métabolique. Affiche présentée à la 12e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Mai 26-28, 2011, Château Bonne Entente, Québec (Qc).
  • Richard C, Couture P, Desroches S, Benjannet S, Seidah NG, Lichtenstein AH, Lamarche B*. Impact of the Mediterranean diet and weight loss on surrogate markers of cholesterol homeostasis in men with the metabolic syndrome. Oral presentation at the Federation of American Societies for Experimental Biology (FASEB). April 9-13, 2011, Washington Convention Center, Washington, DC, USA.  FASEB Journal. Impact Factor: 5.19
  • Royer MM, Lemieux S, Richard C, Desroches S, Couture P, Lamarche B*. Impact of the Mediterranean diet before and after weight loss on eating behavioral traits in men with metabolic syndrome. Poster presented at the Federation of American Societies for Experimental Biology (FASEB). April 9-13, 2011, Washington Convention Center, Washington, DC, USA. FASEB Journal. Impact Factor: 5.19
  • Royer MM, Richard C, Couture P, Desroches S, Lemieux S, Lamarche B*. Diète Méditerranéenne, perte de poids et comportements alimentaires chez l’homme atteint du syndrome métabolique. Conférence présentée à la 11e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. Avril 29-Mai 1, 2010, Château Bonne Entente, Québec (Qc).
  • Richard C, Couillard C, Royer MM, Desroches S, Couture P, Lamarche B*. Impact of the Mediterranean diet and weight loss on plasma cell adhesion molecule concentrations in men with the metabolic syndrome. Poster presented at the Federation of American Societies for Experimental Biology (FASEB). April 24-28, 2010, Anaheim Convention Center, Anaheim, California, USA. FASEB Journal. Impact Factor: 5.19
  • Richard C, Couture P, Charest A, Lamarche B*. Diète Méditerranéenne, perte de poids et caractéristiques du syndrome métabolique. Conférence présentée à la 10e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme. avril 30-Mai 2, 2009, Château Bonne Entente, Québec (Qc).
  • Richard C, Charest A, Couture P, Lamarche B*. Mediterranean diet, weight loss and features of the metabolic syndrome. Oral presentation at the Federation of American Societies for Experimental Biology (FASEB). April 18-22, 2009, Ernest N Morial Convention Center, New-Orleans, Louisiana (LA), USA.